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Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

5-alpha reductase inhibitors may reduce bladder cancer recurrence and improve survival.

Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.

Oral finasteride and dutasteride may negatively affect erectile function in rats.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

5α-reductase inhibitors help shrink the prostate, improve urinary symptoms, and may reduce prostate cancer risk.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.

Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose can help treat hair loss by reducing certain hormones and promoting hair growth.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Store Tectona grandis leaf extracts in slightly acidic, light-protected conditions for best stability.

Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Hair loss drugs may cause sexual issues and infertility in men.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.