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Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.

Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

People with hair loss may have different levels of certain hormones due to changes in hormone processing.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Genetic variations affect dutasteride treatment response for male pattern hair loss.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Women with hair loss have higher androgen levels, while men with early balding have altered androgen ratios.

Women with low SHBG levels and a high 3a-diol G to SHBG ratio are likely to experience female pattern baldness, possibly due to a slight excess of androgens affecting sensitive hair bulbs.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Finasteride safely lowers DHT levels without affecting testosterone.

Finasteride reduces hair growth and is safe for women with excessive hair.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.