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This review examines hormonal influences on acne development and available hormonal therapies but reports no new clinical results.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

This review found no evidence that DHEA improves quality of life or decreases menopausal symptoms in peri- and postmenopausal women, but it may slightly enhance sexual function compared to placebo.

This study suggests that inhibitors of steroidogenic enzymes may have therapeutic potential for certain behavioral disorders linked to dopaminergic hyperfunction, despite concerns about their endocrine impacts.

This study reported higher dihydrotestosterone and testosterone levels in balding Korean and Caucasian subjects compared to non-balding controls, with variations suggesting racial differences in androgen metabolism.

In this study, researchers found that female rats exhibited more pronounced panic-related escape behavior during hypoxia, particularly in the diestrus phase, and that low-dose fluoxetine reduced this behavior, suggesting its potential for managing panic disorder symptoms related to hormonal cycles in women.

This source outlines various antiandrogen and androgen inhibitor drugs used to treat cutaneous disorders of hyperandrogenism, detailing their mechanisms, uses, dosages, and side effects, with emphasis on spironolactone, finasteride, dutasteride, and oral contraceptives.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

This study found that ursolic acid at 50 mg/kg improved biochemical, hormonal, and ovarian histopathological markers in a rat model of PCOS, suggesting its potential as a therapeutic option.

This study found that castration-resistant prostate cancers resistant to CYP17A1 inhibitors may still depend on steroids and could respond to therapies targeting de novo intratumoral steroid synthesis.

This article outlines the clinical features, evaluation, and treatment strategies for androgen excess in polycystic ovary syndrome, highlighting important diagnostic and management approaches but reporting no new research results.

In this study, finasteride dose-dependently inhibited stress-induced increases in allopregnanolone in rats, while enhancing 20alpha-reduction of progesterone without affecting 3alpha-dihydroprogesterone or 11-deoxycorticosterone levels.

This pilot study found that hair metabolome analysis may help differentiate pregnancy complications from healthy pregnancies by revealing significant metabolite differences between trimesters.

This review discusses the current understanding of androgen biosynthesis, mechanisms of action, and their roles in human biology, as well as related congenital and acquired disorders, but it reports no new research findings.

In this animal study, researchers found that finasteride may offer neuroprotective benefits as a post-ischemic treatment for strokes in aged male rats, suggesting its potential as a therapeutic agent in this context.

This review discusses differences in ERβ signaling between rodents and humans and reports no new clinical results; the authors highlight the need for further research in humans before using ERβ agonists clinically.

This study found that Monascus cursory extraction reduced baldness, prostate hyperplasia, and tumor incidence in animal models of androgen-related diseases, suggesting it may be a promising new therapeutic candidate.

This study suggests that in gilthead seabream, DHT is involved in the onset of the meiotic phase of spermatogenesis and influences serum levels of E2 through regulation of aromatase activity.

This chapter reviews the biosynthesis, mechanism of action, and therapeutic effects of testosterone and related androgens, but reports no new research findings.

This study found that vitamin D regulates cholesterol metabolism and may influence prostate cancer development through mechanisms affecting prostate cell growth and sex hormone metabolism.

This study reports that hair samples can be used to track chronic hormone levels, revealing stress, reproductive, and sodium regulation patterns in wildebeest related to environmental factors.

This study found that women with PCOS displayed significantly higher activity of 5alpha-reductase, suggesting an additional role for liver and peripheral tissues in their androgen excess.

This study found that women with PCOS have higher activity of the enzyme 5alpha-reductase, which may contribute to their elevated androgen levels.

This study suggests that the adrenal gland may contribute to prostate cancer treatment resistance and indicates potential steroid production or dependency in ovarian cancer.

This paper reviews the complex pathophysiology of polycystic ovary syndrome, exploring how hormonal and metabolic disturbances contribute to its symptoms and related health risks, but it presents no new findings.

This study found that short durations of heat and specific chemical penetration enhancers significantly improved the delivery of finasteride to human scalp skin and hair follicles.

This study showed that regulation of adipose androgen generation via AKR1C3 may contribute to a cycle of hyperinsulinaemia and lipid accumulation in women with PCOS.

This study found considerable variation in hair shaft proteomic profiles among Caucasian, African-American, Kenyan, and Korean subjects, with individual and site-specific differences observed.

This study used proteomic profiling to reveal significant individual and site-specific differences in human hair shaft proteins, which may improve the differentiation of hair based on ethnic origin and individual identity.

This study found that glucose starvation and hypoxia are physiological triggers of ER stress in in vitro differentiated adipocytes, rather than high concentrations of saturated fatty acids, cholesterol, or proinflammatory cytokines.