research A Mouse Model for Studying Stem Cell Effects on Regeneration of Hair Follicle Outer Root Sheaths
The study found that stem cells and neutrophils are important for regenerating hair follicle structures in mice.
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research Treatment of Actinic Cheilitis with Ingenol Mebutate Gel: Experience in Four Patients
Finasteride for hair loss in young men increases the risk of sexual dysfunction.
research Adverse Effects and Drug Interactions of Biologic Agents
Biologic agents can be effective for rheumatic diseases but have risks like infections and require careful monitoring and patient information.
research Finasteride in Androgenetic Alopecia in Men
Finasteride is effective in stopping hair loss and promoting regrowth in most men with mild side effects.
research Effects of Adipose-Derived Stem Cells and Platelet-Rich Plasma Exosomes on the Inductivity of Hair Dermal Papilla Cells
Exosomes from human fat stem cells can potentially enhance hair growth and survival, providing a new possible treatment for hair loss.
research Phytochemical Analysis of Eclipta Prostrata L. Leaves
Eclipta prostrata leaves contain various compounds with medicinal properties.
research Notes from the Editor Emeritus: Medical Therapy for Hair Loss: What We Know and What We Need to Find Out
Minoxidil and finasteride are effective for male hair loss; minoxidil also helps female hair loss, with some treatments needing more research.
research Supplements That May Counteract Side Effects from Conventional Cancer Therapies
Some supplements may help reduce side effects of cancer treatments in pets.
research Efficacy and Side Effects of Drugs Commonly Used for the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia
Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.
research 5α-Reductase Inhibitors, Antiviral and Anti-Tumor Activities of Some Steroidal Cyanopyridinone Derivatives
Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.
![Synthesis and 5α-Reductase Inhibitory Activity of 8-Substituted Benzo[ƒ]Quinolinones Derived from Palladium Mediated Coupling Reactions](/images/research/2aedba8c-b0ac-4fa3-9ac7-9f375a016bba/small/15581.jpg)
research Synthesis and 5α-Reductase Inhibitory Activity of 8-Substituted Benzo[ƒ]Quinolinones Derived from Palladium Mediated Coupling Reactions
Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.
research Inflammatory Perifollicular Fibrosis And Alopecia
Inflammation around hair follicles leads to hair loss, and treatments should focus on reducing this inflammation and other factors for effectiveness.
research A Comparative In Vivo and In Vitro Evaluation of Hair Growth Potential of Extracts and an Isolate from Petroleum Ether Extract of Cuscuta Reflexa Roxb
Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.
research Effect of Ethanol Extract of Plant Mixture on Hair Regeneration in Human Dermal Papilla Cells and C57BL/6J Mice
A plant mixture extract helped grow hair by boosting cell growth and growth factors while blocking a hair loss-related enzyme.
research Genetics of Alopecia
Different genes are linked to various types of hair loss.
research Pro-Inflammatory Cytokine Cascade in Human Plucked Hair
Anti-IL-1 treatments might help with certain types of hair loss in people with high inflammation.
![Synthesis of Spiro[cyclohexane-1,2'-[2H]indene] Derivatives as Inhibitors of Steroid 5α-Reductase](/images/research/d91300a7-4d66-4d2c-90ac-293b0dbc5ff5/small/21048.jpg)
research Synthesis of Spiro[cyclohexane-1,2'-[2H]indene] Derivatives as Inhibitors of Steroid 5α-Reductase
Compound 15a was effective in inhibiting 5α-reductase.
research Synthesis and Study of Some 17a-Aza-D-Homo Steroids as 5α-Reductase Inhibitors
The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.
research Differential Association Between Cumulative Dose of 5α-Reductase Inhibitors and Mortality
Higher doses of 5α-reductase inhibitors reduce mortality risk, while lower doses increase suicide risk.
research Topical Olive Oil With Downregulation of Stress Factors Protects Mice Skin From Precarious 3600 MHz Electromagnetic Radiation
Topical olive oil protects mice skin from harmful electromagnetic radiation.
research Efficacy of Glucopyranosyldiacylglycerol from Padina Arborescens in Preventing Hair Loss
Padina arborescens and its component MOGG may help prevent hair loss through several actions, including blocking a hair loss-related enzyme.
research Patent Evaluation: Δ-4,6-Steroids as Potent 5α-Reductase Inhibitors
New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.
research Nipple Differentiation in Fetal Male Rats Treated with an Inhibitor of the Enzyme 5α-Reductase: Definition of a Selective Role for Dihydrotestosterone
Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.
research Anti-Androgenic Activity of Myricae Cortex: Isolation of Active Constituents from Bark of Myrica Rubra
The bark of Myrica rubra contains compounds that can block testosterone effects and might help prevent hair loss.
research Treatments for Alopecia Areata: A Systematic Review and Network Meta-Analysis
Some treatments like pentoxifylline with topical corticosteroids might work for alopecia areata, but more research is needed to find the best one.
research Synthesis, Characterization and Evaluation of 5α, 6β-Dihalo Androsterone Derivatives as 5α-Reductase Inhibitors
Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.
research Immunolocalization of 5α-Reductase Isozymes in Acne Lesions and Normal Skin
The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.
research Long-Term Use of 5α-Reductase Inhibitors and the Risk of Male Breast Cancer
Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.
research Molecular Interactions of New Pregnenedione Derivatives
The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.
research ACTH as First Line Treatment for Acute Calcium Pyrophosphate Crystal Arthritis in 14 Hospitalized Patients
ACTH may be an effective first-line treatment for acute calcium pyrophosphate crystal arthritis.