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The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Polycystic ovary syndrome costs the U.S. over $4 billion a year, mainly from treating related health issues.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

AXR3 and SHY2 genes control the growth and timing of root hair development in plants.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

The p53 protein helps control hair follicle shrinking by promoting cell death in mice.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Minoxidil 2% and 5% are common treatments for female pattern hair loss, with other options including anti-androgens, oral contraceptives, and hair transplantation.

New alopecia treatments aim for better results and fewer side effects.

Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.

Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.

STAT5 activation is crucial for starting the hair growth phase.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

South Asian women with PCOS present with different symptoms compared to White women, influenced by ethnicity, obesity, and age.

Forsythiaside-A, a natural substance, can protect against hair loss and is more effective than current treatments, potentially making it a good option for hair loss treatment.