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The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

Anti-glycation treatments might slow skin aging, but more research is needed.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

PPARγ is crucial for skin health but can have both beneficial and harmful effects.

Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.

Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.

Hyaluronic acid and versican are important for skin healing and hair growth and might help in regenerative medicine.

Chitosan and surface-deacetylated chitin nanofibers may help treat hair loss.

More research is needed before using brown fat to treat polycystic ovary syndrome.

Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.

Metal organic frameworks-based scaffolds show promise for tissue repair due to their unique properties.

A PET-CT scan successfully located a hard-to-find Leydig cell tumor in a woman with hormonal symptoms.

Plant sterols have health benefits like lowering cholesterol, but more research is needed to understand their effects and improve their extraction and sustainability.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Physical activity, height, and smoking affect prostate cancer risk.

People with hidradenitis suppurativa are more likely to have bipolar disorder than those with psoriasis or without skin conditions.

ARL15 is important for fat cell development and the release of the hormone adiponectin.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Specialized techniques are needed for hair restoration in individuals with curly Afrocentric hair due to unique challenges.

Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.

Animal research has greatly advanced dermatology.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.