research Hormonal Therapy for Acne
Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.
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research Basics of Hormonal Contraception
Hormonal contraceptives are effective for teens but require careful consideration of side effects and individual health.
research Hair Follicle-Targeting Drug Delivery Strategies for the Management of Hair Follicle-Associated Disorders
New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.
research Triglycerides, Independent of Ferriman Gallwey Score, Is a Main Determinant of Free Testosterone Index in PCOS
High triglyceride levels are a key factor affecting testosterone levels in women with PCOS.
research The Effect of the Antiandrogen 11α-Hydroxyprogesterone on Sebum Production and Cholesterol Concentration of Sebum
The antiandrogen 11α-hydroxyprogesterone effectively reduces skin oil and cholesterol when applied to the skin.
research Simultaneous Determination of 30 Hormones Illegally Added to Anti-Aging Functional Foods Using UPLC-MS/MS Coupled with SPE Clean-Up
New method effectively detects illegal hormones in anti-aging foods.
research Pharmacology of Antiandrogens
Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
research Potential Adverse Effects of Long-Term Testosterone Therapy
Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
research Pathways to Inflammation: Acne Pathophysiology
Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
research Expression of mRNA for Androgen Receptor, 5α-Reductase, and 17β-Hydroxysteroid Dehydrogenase in Human Dermal Papilla Cells
Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
research Gender-Specific Association of Androgenetic Alopecia with Metabolic Syndrome in a Middle-Aged Korean Population
Female hair loss linked to metabolic syndrome, not in males.
research Hirsutism
Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.
research The Rationale for Physiological Testosterone Replacement in Women
Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.
research Spironolactone in Dermatology: Uses in Acne and Beyond
Spironolactone is a low-cost, effective, and generally safe treatment for various skin conditions related to hormones.
research Differential Impact of Environmental Factors on Systemic and Localized Autoimmunity
Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.
research An Updated Overview of Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.
research Hirsutism
Hirsutism is often caused by high male hormone levels and can be treated with lifestyle changes and medications.
research Revisiting Hyper- and Hypo-Androgenism by Tandem Mass Spectrometry
The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.
research Female Pattern Hair Loss
Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.
research Anti-Androgen Therapy in Dermatology: A Review
Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.
research The Medicinal Activity of Lyophilized Aqueous Seed Extract of Lepidium Sativum L. in an Androgenic Alopecia Model
The seed extract of Lepidium sativum L. can potentially treat hair loss, showing effects similar to 5% minoxidil.
research Synthesis and Study of Some 17a-Aza-D-Homo Steroids as 5α-Reductase Inhibitors
The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.
research Anti-TNF Antibody-Induced Psoriasiform Skin Lesions in Patients with Inflammatory Bowel Disease Are Characterised by Interferon-γ-Expressing Th1 Cells and IL-17A/IL-22-Expressing Th17 Cells and Respond to Anti-IL-12/IL-23 Antibody Treatment
Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.
research Trichophyton Tonsurans-Induced Kerion Celsi with Decreased Defensin Expression and Paradoxically Increased Interleukin-17A Production
Terbinafine effectively treated kerion celsi despite disrupted immune responses.
research Biological Profile of Cortexolone 17a-Propionate (CB-03-01), a New Topical and Peripherally Selective Androgen Antagonist
CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.
research Increased Serum Interleukin-17A Levels Correlate with Disease Severity and Poor Prognostic Factors in Patients with Alopecia Areata
Higher IL-17A levels indicate more severe alopecia areata.
research Cortexolone 17a-Propionate: A New Antiandrogen Acting on Hair Dermal Papilla Cells for the Treatment of Androgenic Alopecia
Cortexolone 17a-propionate may be an effective new treatment for hair loss.
research Cortexolone 17a-Propionate: Preclinical Profile of a New Topical, Skin Selective, Steroidal Antiandrogen
Clofazimine may be effective for treating ashy dermatosis.
research Regularities of Change Concentrations of Interleukin-17A, Interleukin-2, and Interleukin-10 in the Blood of People with Alopecia Areata Before and After Treatment with Platelet-Rich Plasma
PRP treatment reduces inflammation and increases interleukin-10 in alopecia areata patients.
research Alopecia Areata Is Characterized by Dysregulation in Systemic Type 17 and Type 2 Cytokines, Which May Contribute to Disease-Associated Psychological Morbidity
Alopecia areata involves immune system imbalances that may lead to depression and anxiety.