research 17β-Estradiol and ICI-182780 Regulate the Hair Follicle Cycle in Mice Through an Estrogen Receptor-α Pathway
Estradiol stops hair growth in mice, but an antagonist can reverse this effect.
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research Anti-Inflammatory and Anti-Hyperplastic Effect of Bazhengsan in a Male Rat Model of Chronic Nonbacterial Prostatitis
Bazhengsan reduces inflammation and tissue growth in chronic prostatitis.
research Hyperandrogenism, Elevated 17-Hydroxyprogesterone and Its Urinary Metabolites in a Young Woman with Ovarian Steroid Cell Tumor, Not Otherwise Specified: Case Report and Review of the Literature
A young woman's symptoms suggested PCOS, but tests and surgery confirmed and treated a rare ovarian tumor, resolving her condition.
research Polycystic Ovarian Morphology Is Associated with Hyperandrogenemia and Insulin Resistance in Women with Polycystic Ovary Syndrome
Women with PCOS and polycystic ovaries have higher male hormone levels and more insulin resistance, especially if they are overweight.
research Glioblastoma Cells Express Crucial Enzymes Involved in Androgen Synthesis: 3β-Hydroxysteroid Dehydrogenase, 17-20α-Hydroxylase, 17β-Hydroxysteroid Dehydrogenase, and 5α-Reductase
Glioblastoma cells can make androgens, which might help the tumor grow.
research Cardiometabolic Risk Factors in Women with Non-Classic Congenital Adrenal Hyperplasia
Women with non-classic congenital adrenal hyperplasia have higher risk for heart and metabolic problems.
research An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation
The estrogen receptor pathway controls hair growth cycles and affects skin cell growth.
research Crystal Structure of 17-Beta-Benzoyloxy-16-Beta-Methylpregna-4,6-Diene-3,20-Dione
A new antiandrogen compound was made and its detailed three-dimensional shape was described.
research A Clinico-Etiological Evaluation of Hirsutism Patients: A Case Series
The conclusion is that hirsutism is strongly linked to PCOS and higher levels of certain hormones, but not to DHEAS, prolactin, cortisol, or TSH.
research Female Hyperandrogenism
The document concludes that managing female hyperandrogenism requires a combination of identifying the cause, lifestyle changes, medication, and cosmetic treatments.
research A Pure Androgen-Secreting Adrenal Cortical Tumor in a 13-Year-Old Female
A 13-year-old girl's masculine symptoms improved after surgery for a rare adrenal tumor that produced male hormones.
research Procedural Hair Restoration: Platelet-Rich Plasma for Hair Loss and Hair Transplant
Platelet-rich plasma (PRP) can help with hair loss and improve hair transplant results.
research Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.
research A 1.6cm Androgen Secreting Ovarian Leydig Cell Tumor Evades Detection on Multiple Imaging Modalities
A woman's small ovarian tumor causing high androgen levels was missed by several scans but found during surgery.
research Syndromes of Severe Insulin Resistance
The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.
research Challenges in the Diagnosis of Simple-Virilizing Congenital Adrenal Hyperplasia: A Case Report
Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.
research Androgen Profiling by Liquid Chromatography–Tandem Mass Spectrometry in Healthy Normal-Weight Ovulatory and Anovulatory Late Adolescent and Young Women
The research found that anovulatory young women have higher androgen and hormone levels than those who ovulate, suggesting immature hormonal regulation rather than a specific condition.
research Non-Classic Congenital Adrenal Hyperplasia
Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.
research The Effect of Simvastatin on Plasma Steroid Hormone Levels in Metformin-Treated Women with Non-Classic Congenital Adrenal Hyperplasia
Simvastatin may help manage symptoms in women with non-classic congenital adrenal hyperplasia by lowering cholesterol and certain hormone levels.
research CYP21A2 Mutations in Women with Polycystic Ovary Syndrome
Mutations in the CYP21A2 gene are not a major factor in causing PCOS.
research Epicardial Fat Thickness in Children with Classic Congenital Adrenal Hyperplasia
Children with classic congenital adrenal hyperplasia have thicker heart fat and more heart and blood vessel risk factors, especially if their condition is not well-controlled.
research 5α-Reductase Activity in the Human Hair Follicle Concentrates in the Dermal Papilla
The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
research Expression of mRNA for Androgen Receptor, 5α-Reductase, and 17β-Hydroxysteroid Dehydrogenase in Human Dermal Papilla Cells
Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
research Compatibility of 17-α-Estradiol, Betamethasone, Finasteride, Melatonin, Prednicarbate, and Spironolactone in TrichoFoam: A Foaming Vehicle for Personalized Alopecia Treatments
TrichoFoam™ effectively delivers multiple hair loss treatments, maintaining their stability and effectiveness.
research Author Response for 'The Comparative Effects Between Long-Term and Short-Term Treatment of Finasteride on Anxiety-Like and Depression-Like Behaviors in Early Senescent Male Rats'
research Achieving Physiologic 17-β-Estradiol Levels in Transgender Females on Estradiol Transdermal Patches and Optimal Dosing
Transgender females can reach their target estrogen levels using estradiol patches, especially if oral treatments fail or if they're at risk for blood clots. Often, the highest dose patch is needed.
research Nonclassic Congenital Adrenal Hyperplasia: An Overview
Nonclassic congenital adrenal hyperplasia is a common genetic disorder that can cause a range of symptoms and requires personalized treatment.
research An Attempt to Assess the Magnitude of Endogenous Androgen Production in a Case of the Adrenogenital Syndrome
A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.
research A Prospective Study of the Prevalence of Nonclassical Congenital Adrenal Hyperplasia Among Women Presenting with Hyperandrogenic Symptoms and Signs
About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.
research Adrenal Steroid Hormone Concentrations in Dogs with Hair Cycle Arrest (Alopecia X) Before and During Treatment with Melatonin and Mitotane
Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.