116 citations,
December 2013 in “European journal of endocrinology” Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.
85 citations,
October 2012 in “Dermatologic Clinics” Alopecia Areata is an autoimmune condition often starting before age 20, with varied treatment success and a need for personalized treatment plans.
63 citations,
May 2011 in “Clinical cancer research” The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.
57 citations,
July 2016 in “The Journal of Sexual Medicine” 5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.
50 citations,
August 1985 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.
48 citations,
January 2011 in “Circulation” Cardiovascular disease deaths decreased but still caused one-third of U.S. deaths in 2007, with high rates of hypertension, smoking, obesity, and diabetes.
47 citations,
February 2019 in “Journal of The American Academy of Dermatology” LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.
46 citations,
December 2014 in “Journal of The American Academy of Dermatology” Premature hair graying in young men is linked to family history, obesity, and smoking.
44 citations,
January 2007 in “Biological & pharmaceutical bulletin” Black pepper leaf extract contains compounds that can block testosterone effects and promote hair growth.
43 citations,
July 2018 in “Journal of The European Academy of Dermatology and Venereology” Finasteride and minoxidil mix works better for hair growth than minoxidil alone, with similar safety.
41 citations,
October 2008 in “The American journal of pathology” Blocking a specific protein signal can make hair grow on mouse nipples.
38 citations,
October 2014 in “British journal of dermatology/British journal of dermatology, Supplement” Bimatoprost solution is effective and safe for long-term use in treating eyelash thinning.
38 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Finasteride effectively improves hair growth and slows hair loss in men with male pattern baldness.
37 citations,
April 2008 in “The Cochrane library” 5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.
36 citations,
November 2009 in “Journal of Investigative Dermatology” Prolactin may affect hair growth differently based on gender and scalp area.
34 citations,
January 2020 in “IEEE Access” A model called PM-DBiGRU was developed for analyzing sentiments in drug reviews, and it performed better than other models, but struggled with complex sentences and situations requiring background knowledge.
34 citations,
February 2012 in “Journal of Cutaneous Pathology” The research found specific signs to diagnose alopecia areata incognito and noted patients generally regrow hair after steroid treatment.
33 citations,
November 2014 in “Military Medicine” The U.S. military's teledermatology program was effective in providing fast and successful skin care in remote locations, preventing unnecessary evacuations.
32 citations,
April 2000 in “Dermatologic Clinics” Skin diseases, especially psoriasis, greatly affect people's quality of life, similar to chronic diseases.
30 citations,
April 2007 in “Dermatologic Clinics” The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.
29 citations,
February 2007 in “Hormone and metabolic research” Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.
28 citations,
September 2014 in “Journal of Clinical Oncology” Men with baldness at the front and top of their head at age 45 may have a higher risk of aggressive prostate cancer.
28 citations,
June 2010 in “European Journal of Cancer” Baldness at age 40 is not linked to a higher risk of aggressive prostate cancer.
25 citations,
March 2017 in “Journal of Dermatological Treatment” Platelet-rich plasma treatment for non-scarring hair loss shows mixed results and needs more research.
25 citations,
August 2010 in “Acta Biomaterialia” Researchers developed a method to grow hair follicle cells for transplantation using a special chip.
24 citations,
January 2003 in “Journal of Investigative Dermatology” Blocking a specific receptor slows down hair loss in mice.
21 citations,
March 2013 in “Cancer Epidemiology, Biomarkers & Prevention” Early-onset baldness is linked to a higher risk of aggressive prostate cancer in African-American men, especially before age 60.
20 citations,
June 2012 in “Human Reproduction” Women with polycystic ovarian syndrome are more likely to have cervical insufficiency, especially South Asian and Black women.
20 citations,
April 2006 in “Dermatologic Clinics” Antiandrogen therapies are beneficial for treating skin and hair conditions related to androgen levels.
16 citations,
March 2011 in “Dermatologic Therapy” Women with greater androgen sensitivity respond better to finasteride for hair loss.