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      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

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      community Why doesn't phase 3 of PP405 start straight away?

      in Chat  14 upvotes 3 weeks ago
      Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.

      community Breezula 6 Month Topline Phase III Results Released

      in Research/Science  167 upvotes 1 month ago
      Breezula shows promising hair growth results, with up to 539% increase in hair count compared to placebo, and regulatory submissions are planned in the US and EU. Users are cautiously optimistic, noting the potential for Breezula to replace finasteride by targeting DHT without systemic effects.

      community The ANSM is trying to ban Finasteride

      in Research/Science  110 upvotes 7 months ago
      France is considering reviewing finasteride and dutasteride due to concerns about their safety, but a ban in the EU is unlikely due to regulatory hurdles. Many users express frustration over the potential ban, emphasizing the effectiveness of finasteride for hair loss and criticizing the influence of anecdotal evidence on public health policy.