September 2023 in “Nature Communications” In this animal study, the researchers found that biodegradable extracellular matrix scaffolds accelerated wound healing and enhanced hair follicle neogenesis in mice, suggesting a role for immune systems in tissue regeneration.
August 2026 in “Cell Insight” This review discusses how regulatory T cells may also promote tissue regeneration through specialized pathways, in addition to their traditional role in maintaining immune tolerance, but reports no new experimental results.
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January 2025 in “Genes & Diseases” This review highlights that T cells are crucial in regulating hair follicle regeneration and their disruption can lead to alopecia, providing insights into hair disorders related to T cell immune balance and hair follicle regeneration.
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March 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, the researchers reported that using a biodegradable ECM scaffold for large-area wound regeneration accelerated wound coverage and improved hair follicle neogenesis by activating the adaptive immune system.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study indicates that a helminth-derived protein, TGF-β mimic, may accelerate wound healing and promote regenerative processes in skin tissue by interacting with TGF-β receptors.
