Beyond Immune Suppression: Regenerative Programs in Regulatory T Cells

    August 2026 in “ Cell Insight ”
    Yannan You, Xianting Hu, Yueqing Xue, Zhi Liu
    Studysummary This review discusses how regulatory T cells may also promote tissue regeneration through specialized pathways, in addition to their traditional role in maintaining immune tolerance, but reports no new experimental results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on sciencedirect.com →
    Discuss this study in the Community →

    Research cited in this study 6

    1. Regulatory T Cells in Skin Utilize the Cxcr4-Cxcl12 Axis to Promote Hair Follicle Regeneration Cell Reports · 2025
    2. CD80 on Skin Stem Cells Promotes Local Expansion of Regulatory T Cells Upon Injury to Orchestrate Repair Within an Inflammatory Environment Immunity · 2024
    3. Regulatory T Cells in Skin Mediate Immune Privilege of the Hair Follicle Stem Cell Niche Science Immunology · 2024
    4. Local and Systemic Mechanisms That Control the Hair Follicle Stem Cell Niche Nature Reviews Molecular Cell Biology · 2023
    5. Regulatory T-Cells: Potential Regulator of Tissue Repair and Regeneration Frontiers in Immunology · 2018
    6. Regulatory T Cells in Skin: Role of Foxp3+ CD4+ Tregs in Skin Homeostasis and Immune Tolerance Immunology · 2017