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Immunoreactivity of the SARS-CoV-2 Entry Proteins ACE-2 and TMPRSS-2 in Murine Models of Hormonal Manipulation, Aging, and Cardiac Injury

research Immunoreactivity of the SARS-CoV-2 Entry Proteins ACE-2 and TMPRSS-2 in Murine Models of Hormonal Manipulation, Aging, and Cardiac Injury

5 citations , December 2021 in “Scientific Reports”

Age affects how certain proteins involved in COVID-19 infection are expressed in mice, but sex hormones and heart injury do not.

research The Immune Response to COVID-19: Does Sex Matter?

15 citations , April 2022 in “Immunology”

Men and women get COVID-19 at similar rates, but men tend to get sicker and have a higher risk of dying, while women usually have stronger immune responses and vaccine reactions.

research Integrated Lipidomics in the Secreted Phospholipase A2 Biology

11 citations , February 2011 in “International Journal of Molecular Sciences”

Different sPLA2 enzymes have unique roles in phospholipid metabolism and biological processes.

research From Bedside to Bench: Regulation of Host Factors in SARS-CoV-2 Infection

4 citations , April 2021 in “Experimental and Molecular Medicine”

The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.

research Sex Hormones in SARS-CoV-2 Susceptibility: Key Players or Confounders?

8 citations , December 2022 in “Nature Reviews Endocrinology”

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

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community So does oral minoxidil age your skin or not

in Minoxidil 45 upvotes 1 year ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.

community 21 year old jawal lal mehru (first prime minister of india) writing letter to his father about hair loss.

in Technology 707 upvotes 7 months ago

Hair loss struggles and treatments like finasteride and minoxidil. The emotional impact and limited effectiveness of these treatments are discussed.

community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 44 upvotes 1 year ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

community Is the Ru58841 hype justified?

in Treatment 18 upvotes 1 year ago

RU58841 is debated for hair regrowth, with some users reporting no benefits and potential side effects, while others claim success when combined with dutasteride. Many suggest safer, well-researched treatments like finasteride and minoxidil for hair loss management.

community Scientists have found that a naturally occurring sugar in humans and animals could be used as a topical treatment for male pattern baldness | In the study, mice received 2dDR-SA gel for 21 days, resulting in greater number of blood vessels and an increase in hair follicle length and denseness

in Research/Science 640 upvotes 1 year ago

Scientists discovered a sugar gel, 2dDR-SA, that increased hair growth in mice. Users discussed its potential, comparing it to other treatments like Minoxidil and finasteride.

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