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Immunoreactivity of the SARS-CoV-2 Entry Proteins ACE-2 and TMPRSS-2 in Murine Models of Hormonal Manipulation, Aging, and Cardiac Injury

research Immunoreactivity of the SARS-CoV-2 Entry Proteins ACE-2 and TMPRSS-2 in Murine Models of Hormonal Manipulation, Aging, and Cardiac Injury

5 citations, December 2021 in “Scientific Reports”

Age affects how certain proteins involved in COVID-19 infection are expressed in mice, but sex hormones and heart injury do not.

research The Immune Response to COVID-19: Does Sex Matter?

15 citations, April 2022 in “Immunology”

Men and women get COVID-19 at similar rates, but men tend to get sicker and have a higher risk of dying, while women usually have stronger immune responses and vaccine reactions.

research From Bedside to Bench: Regulation of Host Factors in SARS-CoV-2 Infection

4 citations, April 2021 in “Experimental and Molecular Medicine”

The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.

research Sex Hormones in SARS-CoV-2 Susceptibility: Key Players or Confounders?

8 citations, December 2022 in “Nature Reviews Endocrinology”

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

research Autotaxin-LPA Signaling Contributes to Obesity-Induced Insulin Resistance in Muscle and Impairs Mitochondrial Metabolism

45 citations, August 2018 in “Journal of Lipid Research”

Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.

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community So does oral minoxidil age your skin or not

in Minoxidil 41 upvotes 9 months ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.

community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 47 upvotes 7 months ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

community Is the Ru58841 hype justified?

in Treatment 17 upvotes 2 months ago

RU58841 is debated for hair regrowth, with some users reporting no benefits and potential side effects, while others claim success when combined with dutasteride. Many suggest safer, well-researched treatments like finasteride and minoxidil for hair loss management.

community Scientists have found that a naturally occurring sugar in humans and animals could be used as a topical treatment for male pattern baldness | In the study, mice received 2dDR-SA gel for 21 days, resulting in greater number of blood vessels and an increase in hair follicle length and denseness

in Research/Science 636 upvotes 5 months ago

Scientists discovered a sugar gel, 2dDR-SA, that increased hair growth in mice. Users discussed its potential, comparing it to other treatments like Minoxidil and finasteride.

community Hair Loss Treatment Iceberg Chart

in Satire 1376 upvotes 3 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, RU58841, ass hair transplant, topical Viagra, castration, and transitioning to female. A user mentions an experimental drug called M4U-5 (Mousteride) that turns you into a mouse.

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