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GlossaryInflammatory Mediators

substances released to initiate and regulate inflammation

Inflammatory mediators are substances released by immune cells and other tissues in response to injury or infection, which help to initiate and regulate the inflammatory response. These can include cytokines, prostaglandins, and histamines, among others, and they play crucial roles in signaling pathways that lead to symptoms like redness, swelling, and pain. Understanding these mediators is essential for developing treatments for conditions like alopecia, where inflammation can contribute to hair loss.

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research Saponins of Paris Polyphylla for the Improvement of Acne: Anti-Inflammatory, Antibacterial, Antioxidant and Immunomodulatory Effects

April 2024 in “Molecules/Molecules online/Molecules annual”

Paris polyphylla saponins may effectively treat acne due to their antibacterial and anti-inflammatory properties.

research 26SCS-Loaded SilMA/Col Composite Sponge with Well-Arranged Layers Promotes Angiogenesis-Based Diabetic Wound Repair by Mediating Macrophage Inflammatory Response

April 2024 in “Molecules/Molecules online/Molecules annual”

The composite sponge helps heal diabetic wounds by reducing inflammation and promoting new blood vessel growth.

research What Causes Hidradenitis Suppurativa?—15 Years After

78 citations, October 2020 in “Experimental Dermatology”

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

research Identification of Immune Microenvironment Changes, Immune-Related Pathways and Genes in Male Androgenetic Alopecia

September 2023 in “Medicine”

The research suggests immune system changes and specific gene expression may contribute to male hair loss, proposing potential new treatments.

research Remission of Hair Loss and Induction of Hair Regrowth by Botulinum Neurotoxin A in Mice

May 2008 in “Toxicon”

Botulinum toxin A helped stop hair loss and grow new hair in mice.

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community What would be an ideal diet for promoting health for what's left/regrowth?

in Question 38 upvotes 5 years ago

The conversation discusses an ideal diet for promoting hair health, emphasizing biotin, collagen, vitamins C and E, zinc, selenium, anti-inflammatory foods, and blood circulation. It also mentions using finasteride, minoxidil, and dermarolling for hair regrowth.

community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 122 upvotes 6 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community First 3 pics are at 6 months .5 mg fin daily, last 3 are 13 months

in Progress Pictures 74 upvotes 10 months ago

The user experienced improved hair at 6 months using 0.5 mg finasteride daily but noticed more scalp visibility and potential hair loss at 13 months, questioning if this was due to shedding or the treatment not working. Some respondents suggested the possibility of a shed or scalp inflammation, while others observed improvements or advised checking for underlying scalp conditions.

community 25 months. Dutasteride, RU58841, Minoxidil, Microneedling, Nizoral, T/GEL, fixing vitamin D levels

in Progress Pictures 2245 upvotes 3 years ago

User "manlycoffee" shares 25-month progress using Dutasteride, RU58841, Minoxidil, Microneedling, Nizoral, T/GEL, and fixing vitamin D levels for hair loss. Users discuss sources, experiences, and side effects of treatments.

community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 7 months ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

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