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Glossary Pro-inflammatory markers

substances indicating inflammation in the body

Pro-inflammatory markers are substances in the body that indicate the presence of inflammation. These markers, such as cytokines and C-reactive protein (CRP), are produced by the immune system and can be measured in blood tests to help diagnose and monitor conditions like infections, autoimmune diseases, and even hair loss disorders like alopecia.

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Research

5 / 1000+ results

Epidermal Keratinocytes Initiate Wound Healing and Pro-Inflammatory Immune Responses Following Percutaneous Schistosome Infection

research Epidermal keratinocytes initiate wound healing and pro-inflammatory immune responses following percutaneous schistosome infection

39 citations , January 2015 in “International journal for parasitology/International Journal for Parasitology”

This study found that Schistosoma mansoni cercariae stimulate epidermal keratinocytes in mice, initiating pro-inflammatory responses and barrier repair mechanisms akin to those in wound healing.

research Pro-inflammatory Vδ1+T-cells infiltrates are present in and around the hair bulbs of non-lesional and lesional alopecia areata hair follicles

23 citations , September 2020 in “Journal of Dermatological Science”

This pilot study suggests that skin-resident γδT-cells may play a significant role in the early stages of alopecia areata pathogenesis, indicating a potential new target for therapeutic management.

Advanced Glycation End-Products Inhibit Mesenchymal-Epidermal Interaction by Up-Regulating Proinflammatory Cytokines in Hair Follicles

research Advanced glycation end-products inhibit mesenchymal-epidermal interaction by up-regulating proinflammatory cytokines in hair follicles

3 citations , July 2015 in “European Journal of Dermatology”

This abstract discusses the role of advanced glycation end-products in aging-related skin damage, but does not provide new findings on their impact on alopecia.

research The effects of methylated flavonoids on depression-like activity and pro-inflammatory cytokine thresholds in mice induced by repeated finasteride administration

1 citations , January 2021 in “European Journal of Inflammation”

In this study, naringenin and its methylated derivatives reduced depression-like behaviors and inflammation markers in mice exposed to finasteride, suggesting their potential as effective and safe anti-depressive agents.

research Common Skin Diseases and Metabolic Syndrome: A Proinflammatory Chemokine Perspective

April 2026 in “Metabolites”

This narrative review explores the strong association between various chronic inflammatory skin diseases and metabolic syndrome, emphasizing shared inflammatory pathways and chemokine involvement, though the precise molecular connections remain partially understood.

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Community Join

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community Microneedling aftercare advice

4 upvotes 4 years ago

Microneedling aftercare involves using saline water instead of sea water, and avoiding hyaluronic acid due to its potential pro-inflammatory effects. Users suggest using jojoba oil as a carrier for essential oils like rosemary and lavender, and combining microneedling with minoxidil for better hair regrowth results.

community Been on fin for 3 months, and Min for 4. How am I doing?

5 upvotes 2 weeks ago

The user has been using finasteride for 3 months and minoxidil for 4 months for hair loss. It's too early to see results, and shedding is likely occurring.

community Short Peptides for Hair Loss: anyone tried any of these?

14 upvotes 5 months ago

Various peptides are discussed for treating male pattern baldness, with some available for topical use like GHK-Cu and Ac-KGHK, while others remain in research stages. Users are interested in experiences and sourcing these treatments.

community 5 months in.. planning to do a transplant @ the 1 year mark

in Is this regrowth? 22 upvotes 1 year ago

The user is using a regimen of dutasteride, oral and topical minoxidil, Nutrafol, and keto shampoo for hair regrowth, with plans for a hair transplant at the one-year mark. Users suggest adjusting treatments due to scalp inflammation and discuss the potential addition of RU58841, while noting impressive results so far.

community Do PUFA's accelerate hair loss? Is this tweet accurate?

4 months ago

PUFA foods like salmon and walnuts are healthy and do not accelerate hair loss. There is no evidence linking PUFAs to hair loss, and claims suggesting otherwise lack scientific support.

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Learn

6 / 801 results

learn Omega 3

Is the omega-3 to omega-6 ratio in your diet feeding your hair problem without you knowing? Nutrition sources describe a lopsided omega-6 to omega-3 intake as pro-inflammatory, but no published human study shows that the dietary ratio changes 5-alpha reductase, scalp DHT or hair loss; the one relevant trial tested a commercial omega-3/6 plus antioxidant supplement in 120 women, not a change in dietary fat ratio.

learn sh-Polypeptide-7

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Stem Cell Factor

learn Hydrocortisone

a synthetic cortisol used for anti-inflammatory effects

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Clinics

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