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GlossaryPioglitazone

medication for type 2 diabetes that increases insulin sensitivity

Pioglitazone, also known by the brand name Actos, is a medication used to manage type 2 diabetes. It works by increasing the body's sensitivity to insulin, helping to control blood sugar levels. While primarily used for diabetes, it has also been studied for potential benefits in other conditions, including certain types of hair loss like alopecia, due to its anti-inflammatory and insulin-sensitizing properties.

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Chitosan Nanoparticles for Topical Drug Delivery in Chemotherapy-Induced Alopecia: A Comparative Study of Five Repurposed Pharmacological Agents

research Chitosan Nanoparticles for Topical Drug Delivery in Chemotherapy-Induced Alopecia: A Comparative Study of Five Repurposed Pharmacological Agents

July 2025 in “Pharmaceuticals”

Phenobarbital-loaded chitosan nanoparticles are promising for preventing hair loss from chemotherapy.

research What's New in Cicatricial Alopecia?

16 citations, January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”

New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.

research Unlocking Finasteride's Potential Via Carboxymethyl-Beta-Cyclodextrin Inclusion Complex For Androgenic Alopecia

March 2025 in “Carbohydrate Polymer Technologies and Applications”

The new method improves finasteride's effectiveness for hair loss treatment.

research From Plants to Wound Dressing and Transdermal Delivery of Bioactive Compounds

July 2023 in “Plants”

Plant-based compounds can improve wound dressings and skin medication delivery.

research A Randomized Placebo-Controlled Study on the Effects of Pioglitazone on Cortisol Metabolism in Polycystic Ovary Syndrome

24 citations, April 2008 in “Fertility and sterility”

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

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community You will lose hair if your prostaglandins aren't in balance

in Research/Science 58 upvotes 4 months ago

Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

community Hair Loss & Lipids: Why you have sebderm, folliculitis, LPP, inflammation, etc...

in Research/Science 133 upvotes 4 months ago

Excess sebum rich in cholesterol and triglycerides can lead to hair loss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.

community DUPA/Retrograde might not be DHT based...GET A BIOPSY QUICK or permanent Hair Loss!

in Research/Science 40 upvotes 5 months ago

DUPA and retrograde alopecia may not be solely DHT-based, and a biopsy is crucial for accurate diagnosis and treatment. Treatments mentioned include dutasteride, oral minoxidil, pioglitazone, clobetasol, calcipotriol, ketoconazole, and doxycycline, depending on the specific condition.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 10 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community here is why isotretinoin might cause hair loss and maybe why dupa happens.

in Research/Science 7 upvotes 2 years ago

Isotretinoin may cause hair loss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hair loss.

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