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Research

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Site of Beige and Leaden Pigment Gene Expression Determined by Recombinant Embryonic Skin Grafts and Aggregation Mouse Chimaeras Employing Sash Homozygotes

research Site of beige (bg) and leaden (ln) pigment gene expression determined by recombinant embryonic skin grafts and aggregation mouse chimaeras employing sash (W^sh) homozygotes

7 citations , October 1985 in “Genetics Research”

This study found that in chimaeric mice models, the pigment distribution and pattern were influenced by the sash genotype, demonstrating the melanocyte-autonomous nature of the beige and leaden loci.

research Transgneic Endothelin 3 Regulates Murine Pigment Production and Coat Color

October 2017

This study found that transgenic expression of Endothelin 3 in mice can maintain a dark pigmentation phenotype independently of Mc1r signaling by regulating melanogenic genes.

research Differential Gene Expression Screening Between Black and Gray Hairs Using Subtractive Library and DNA Chip

January 2004 in “Linchuang pifuke zazhi”

This study identified specific genes that are more abundantly expressed in black hair than in gray hair, with black hair displaying higher expression of pigment-related proteins and gray hair showing increased expression of keratin-related genes.

research CDH3 gene related hypotrichosis and juvenile macular dystrophy – A case with a novel mutation

9 citations , June 2017 in “American journal of ophthalmology. Case reports”

This case report identifies a novel CDH3 gene mutation associated with hypotrichosis with juvenile macular dystrophy in a 13-year-old Turkish girl, highlighting implications for future genetic analysis and counseling.

research Amelioration by Copper Supplementation of Mutant Gene Effects in the Crinkled Mouse

23 citations , August 1975 in “Experimental Biology and Medicine”

This study found that supplementing pregnant and lactating mice with high dietary copper improved survival and physical traits in mice carrying the crinkled mutation, suggesting copper's role in modulating gene expression.

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Community Join

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community Say goodbye to facial hair development Dutasteride

39 upvotes 1 month ago

A 19-year-old started Dutasteride at 17 to combat aggressive hair thinning, which halted his facial hair development despite having strong beard genetics. He also used oral and topical Minoxidil without success for facial hair, and the discussion highlights the impact of DHT blockers on beard growth.

community Making your own RT1640 in China

4 years ago

RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

community Scared of Twink death due to minoxidil

in Minoxidil 9 months ago

A 19-year-old is considering switching from topical to oral minoxidil to combat hair loss, despite concerns about increased body hair. They are currently using minoxidil, ketoconazole shampoo, and dutasteride, and are willing to accept the trade-off of more body hair for better scalp hair growth.

community M22 Minoxidil twice daily on the temples for 7 months, Finasteride 0.5 mg ed for 3 months

in Progress Pictures 115 upvotes 1 year ago

Minoxidil helped with temple regrowth, and finasteride improved overall hair appearance and stopped further hair loss. Minoxidil was also applied to eyebrows and eyelids, with noticeable gains, but was stopped on the beard due to bloating.

community New vellus hairs? 2.5min .5dut

in Is this regrowth? 9 upvotes 1 month ago

The user is experiencing new vellus hair growth after using 0.5 mg dutasteride daily and 2.5 mg minoxidil daily for over two months, following a previous regimen with minoxidil and finasteride. They note significant growth in eyelashes, eyebrows, and facial hair, attributing the changes to the medications rather than lifestyle adjustments.

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Experts

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22
Hair System Specialist
Jane Genesi
Marlton, PA, United States

Learn

5 / 801 results

learn Scalp Micropigmentation

scalp tattoos to mimic the appearance of light stubble

What pigments are used in scalp micropigmentation? Providers describe SMP pigments as organic, vegan and formulated for the scalp, but these are supplier and marketing descriptions rather than verified specifications, and clinics contradict each other on colour change and chemical content.
Are the pigments used in scalp micropigmentation safe? Providers describe SMP pigments as safe, medical-grade and made for the scalp, but those are supplier and clinic descriptions rather than regulatory approvals: no colour additive is approved for injection into the skin, and allergic reactions to tattoo pigment are documented.

learn Stem Cell Factor

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

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Clinics

6 / 31 results

All 31 clinic results →

Jane Genesi