August 2026 in “Molecules” This study found that pungenin from Picea wilsonii Mast. showed potential in promoting hair regeneration and protecting hair follicles in a DHT-induced androgenetic alopecia mouse model.
9 citations
,
June 2023 in “Cells” This review summarizes recent findings on how the dysregulated PI3K/Akt/mTOR pathway contributes to immune-mediated inflammatory skin disorders and discusses the potential of natural products, synthetic compounds, and biologic agents in their treatment. However, it emphasizes the need for further research to develop effective therapies.
August 2025 in “Current Issues in Molecular Biology” This study demonstrated that Periplaneta americana extract significantly promoted hair regeneration in depilated mice by enhancing superoxide dismutase activity, upregulating vascular endothelial growth factor, modulating the FOXO/PI3K/AKT pathway, and restoring skin microbiome balance, suggesting its potential as a novel therapeutic candidate for alopecia.
1 citations
,
November 2025 in “Clinical and Experimental Medicine” This review highlights the emerging role of long non-coding RNAs (lncRNAs) in dermatology, suggesting that lncRNAs significantly impact signaling pathways involved in normal skin functions and skin diseases, offering potential as biomarkers and therapeutic targets.
December 2025 in “Journal of Ovarian Research” This study found that multiple vitamins, including B6, increased the number of growing follicles in newborn mouse ovaries in vitro. VB6 promoted primordial follicle activation via the PI3K/Akt signaling pathway in both cultured mouse and human ovarian tissues.
