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5 / 10 resultslearn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn Epidermal Growth Factor
learn Caffeine
the stimulant you know and love can be used topically to stimulate hair
learn Vascular Endothelial Growth Factor
Research
5 / 1000+ resultsresearch Lipid Nanoparticles for Topical and Transdermal Application for Alopecia Treatment: Development, Physicochemical Characterization, and In Vitro Release and Penetration Studies
Lipid nanoparticles show promise for delivering alopecia treatments to the skin.
research Ethnic Differences in Skin Physiology, Hair Follicle Morphology, and Follicular Penetration of Topically Applied Substances
Ethnic differences in skin and hair affect penetration minimally, but cultural habits matter in product development.
research Lipid Nanoparticles for Topical and Transdermal Application for Alopecia Treatment: Development, Physicochemical Characterization, and In Vitro Release and Penetration Studies
New lipid nanoparticles show promise for delivering hair loss treatments but need improvement for better skin penetration.
research Methods and Models for the Investigation of the Uptake of Nanoparticles into Hair Follicles
Nanoparticles can effectively enter hair follicles and stimulate immune responses, supporting potential transfollicular vaccination.
research Developing Formulations Designed to Deliver Antiseptic Agents to Target Sites Within the Skin
Nanoemulsions can effectively deliver antiseptic agents deep into the skin.
Community Join
5 / 222 resultscommunity Has Anyone Heard About Ethossomal Finasteride? 6x Finasteride Delivery in Hair Folicule?
A user is considering switching from oral to topical finasteride to reduce systemic DHT impact and is exploring ethossomal finasteride for better skin penetration and potential hair regrowth. They found ethossomal finasteride in Brazil and are seeking opinions on its effectiveness compared to other topical delivery methods.
community What is the real impact of dutasteride on neurosteroids? A little review of 2 scientific datas
Dutasteride at 0.5 mg/day does not significantly alter allopregnanolone levels, but higher doses (2.5 mg/day) do. Dutasteride may also have anti-neuroinflammatory effects, but the impact on neurosteroids is still debated.
community Switching RU vehicle due to scalp irritation – anyone tried low-EtOH + squalane / emu oil?
The user is experiencing scalp irritation from using RU58841 with a 70% ethanol and 30% propylene glycol vehicle and is considering switching to a less irritating vehicle, such as 30% ethanol with 70% squalane or emu oil. They are seeking feedback on the effectiveness and irritation levels of these alternative carriers.
community Pyrilutamide vs enzalutamide. Same thing?( Especially for biochemists, farmacologists)
Researching whether pyri and enza, which are stereoisomers of each other, share the same features related to CNS penetration/GABA Inhibition; safety and efficacy when used topically at 0.5-1%; and cost comparison between the two treatments.
community Verteporfin and Microneedling
Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.