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    GlossaryPhosphodiesterase (PDE)

    enzyme that breaks down cyclic nucleotides in cells

    Phosphodiesterase (PDE) is an enzyme that plays a crucial role in cellular signaling by breaking down cyclic nucleotides like cAMP and cGMP, which are molecules that transmit signals inside cells. By regulating the levels of these cyclic nucleotides, PDEs help control various physiological processes, including heart rate, inflammation, and even hair growth.

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      community Hair Loss “Cure” for Inflammation: Topical Roflumilast

      in Research/Science  31 upvotes 5 days ago
      Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

      community Just started ru58841, ask me anything.

      in Research/Science  14 upvotes 1 week ago
      The conversation discusses a hair loss treatment regimen including oral dutasteride, oral minoxidil, tadalafil, and the recent addition of RU58841. The user shares experiences with these treatments, noting significant hair regrowth and stabilization, and discusses the cost and preparation of RU58841.

      community Hair Loss Treatment Iceberg Chart

      in Satire  1382 upvotes 4 years ago
      Hair loss treatments discussed include Minoxidil, Finasteride, RU58841, ass hair transplant, topical Viagra, castration, and transitioning to female. A user mentions an experimental drug called M4U-5 (Mousteride) that turns you into a mouse.