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Glossary Parathyroid Hormone-CBD

modified parathyroid hormone targets collagen in bone for treatment

Parathyroid Hormone-CBD (PTH-CBD) is a modified form of parathyroid hormone that includes a collagen binding domain. This modification allows the hormone to specifically target and bind to collagen in the bone matrix, potentially enhancing its effectiveness in treating conditions like osteoporosis by promoting bone growth and repair more efficiently.

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research Treatment and prevention of chemotherapy-induced alopecia with PTH-CBD, a collagen-targeted parathyroid hormone analog, in a non-depilated mouse model

20 citations , September 2013 in “Anti-Cancer Drugs”

In this study, PTH-CBD effectively prevented and partially reversed chemotherapy-induced alopecia in mice, with pretreatment offering a better cosmetic outcome compared to therapeutic administration after hair loss onset.

research A Single Injection of the Anabolic Bone Agent, Parathyroid Hormone–Collagen Binding Domain (PTH–CBD), Results in Sustained Increases in Bone Mineral Density for up to 12 Months in Normal Female Mice

23 citations , July 2012 in “Calcified Tissue International”

In this study, a single dose of PTH–CBD produced a sustained increase in bone mineral density for up to a year in mice, indicating its potential as an osteoporosis treatment.

research Therapy for Alopecia Areata in Mice by Stimulating the Hair Cycle with Parathyroid Hormone Agonists Linked to a Collagen-Binding Domain

12 citations , November 2015 in “Journal of Investigative Dermatology Symposium Proceedings”

PTH-CBD helps reduce hair loss in mice by stimulating hair growth directly.

research Parathyroid hormone linked to a collagen binding domain promotes hair growth in a mouse model of chemotherapy-induced alopecia in a dose-dependent manner

8 citations , April 2014 in “Anti-Cancer Drugs”

In this study, PTH–CBD displayed dose-dependent effects in reducing hair loss and enhancing hair regrowth in a mouse model of chemotherapy-induced alopecia.

research Treatment of Alopecia Areata in Mice by Stimulating the Hair Follicles Using Parathyroid Hormone Agonists Linked to a Collagen Binding Domain

January 2015 in “Journal of clinical & experimental dermatology research”

This study found that treatment with PTH-CBD stimulated hair growth in mice with alopecia areata, with increased levels of beta catenin indicating activation of the Wnt pathway.

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community My muscles & butt are disappearing on finas, and I’m only taking it because my hair was vanishing too. Help! Details below.

in Finasteride/Dutasteride 7 upvotes 5 years ago

A 39 year old female who has been taking finasteride for 1.5 months and is experiencing side effects such as muscle and butt shrinkage, and weight loss despite still having tight clothing. The user is seeking advice from those with knowledge of bodybuilding and hormones to help figure out the issue.

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