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GlossaryHyperparathyroidism

condition where parathyroid glands overproduce hormone regulating calcium levels

Hyperparathyroidism is a condition where the parathyroid glands produce too much parathyroid hormone (PTH). This hormone regulates calcium levels in the blood, and its overproduction can lead to elevated calcium levels, potentially causing symptoms like bone pain, kidney stones, fatigue, and depression. There are two main types: primary hyperparathyroidism, often caused by a benign tumor on the gland, and secondary hyperparathyroidism, usually resulting from another condition like chronic kidney disease.

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research Case Report: Exceptional Association of Leydig Cell Ovarian Tumor and Primary Hyperparathyroidism in a Postmenopausal Patient

May 2021 in “Journal of the Endocrine Society”

A woman with a rare ovarian tumor and hyperparathyroidism improved after surgery, highlighting the need for reporting unusual cases to understand and manage rare diseases.

research Occurrence of Klinefelter Syndrome Mosaic 45,X/46,XY/47,XXY/48,XXYY/48,XXXY and Primary Hyperparathyroidism

March 2021 in “AACE clinical case reports”

A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.

research Normalization of Mineral Ion Homeostasis by Dietary Means Prevents Hyperparathyroidism, Rickets, and Osteomalacia, But Not Alopecia in Vitamin D Receptor-Ablated Mice

519 citations , October 1998 in “Endocrinology”

Diet can prevent bone issues but not hair loss in mice lacking vitamin D receptors.

research Normalization of Mineral Ion Homeostasis by Dietary Means Prevents Hyperparathyroidism, Rickets, and Osteomalacia, But Not Alopecia in Vitamin D Receptor-Ablated Mice

119 citations , October 1998 in “Endocrinology”

Diet can prevent bone issues but not hair loss in mice lacking vitamin D receptors.

research Parathyroid Adenoma with Coeliac Disease: Primary or Quaternary Hyperparathyroidism?

2 citations , January 2012 in “PubMed”

A gluten-free diet and surgery fixed the girl's calcium levels and started puberty.

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