6 citations
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December 2019 in “Dermatologic Therapy”
This study evaluated oraldutasteride for male androgenetic alopecia in a real-world setting, reporting that it effectively improved hair conditions in 90% of patients using monotherapy, with a good safety profile, particularly at low doses.
5 citations
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January 2020 in “Skin appendage disorders”
This study found that oraldutasteride increased hair count more than intralesional administration in androgenetic alopecia, but more research is needed for a reliable comparison.
1 citations
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July 2024 in “Journal of the European Academy of Dermatology and Venereology”
This review concludes that oraldutasteride has the highest evidence level for stabilizing frontal fibrosing alopecia and should be used as a first-line treatment until more randomized controlled trials are conducted.
March 2026 in “Revista Ibero-Americana de Humanidades, Ciências e Educação”
This study reports that perioperative use of dutasteride, both orally and through mesotherapy, may enhance hair graft survival and reduce shock loss in patients undergoing hair transplantation for androgenetic alopecia.
The user experienced hair recovery using oraldutasteride 0.5 mg and oral minoxidil 5 mg daily, considering increasing dutasteride dosage but concerned about cost and effectiveness. They noted progress and discussed alternatives like hair transplants and other medications.
The user is using oraldutasteride, oral minoxidil, topical minoxidil, finasteride solution, tazarotene, calcipotriol, and a peptide serum for hair loss but is concerned about continued hair shedding. They are advised to stop smoking as it may worsen hair loss and to give the treatments more time to work.
The user has used oralDutasteride and Minoxidil for two years without regrowth, despite trying Finasteride and supplements. They consider increasing Minoxidil, adding microneedling, and switching medications, while others suggest RU58841, a hair transplant, or checking for other hair loss causes.
Oraldutasteride 0.5 mg combined with oral minoxidil 2.5 mg is highly effective for male androgenetic alopecia, showing over 60% improvement and 98% stabilization at 6 months, with low adverse event rates. Patients with severe baseline conditions respond better and faster to this treatment.
OralDutasteride and topical Minoxidil significantly improved hair regrowth over nine months. Other users shared mixed results and side effects with treatments like oral Minoxidil and Finasteride.
Is metformin used topically for hair loss, or only as an oral tablet?Approved metformin products are oral tablets only; there is no approved topical metformin for hair loss. Published human reports of topical use are a handful of uncontrolled, pharmacy-compounded case reports in scarring alopecia, and the most-cited clinical series actually used the oral drug.
Is pyrilutamide a safer alternative to oral antiandrogens like finasteride?Pyrilutamide (KX-826) is an unapproved, investigational topical antiandrogen whose safety data come from short-term sponsor announcements, not peer-reviewed studies. No study has compared it with finasteride, so there is no evidence that it is safer.