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research Synthesis of 5,6,6-[2H3]finasteride and quantitative determination of finasteride in human plasma at picogram level by an isotope-dilution mass spectrometric method

20 citations , December 1995 in “Journal of Chromatography B: Biomedical Sciences and Applications”

Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.

research High-performance liquid chromatographic determination of finasteride in human plasma using direct injection with column switching

29 citations , February 1996 in “Journal of Chromatography B: Biomedical Sciences and Applications”

This study developed a fully automated HPLC method for accurately quantifying finasteride in human plasma, achieving a detection limit of 1 ng/ml with validated application in pharmacokinetic studies.

research 5α-reductase inhibitors

5 citations , January 2001 in “Advances in protein chemistry”

This chapter reviews recent advances in 5α-reductase inhibitors for treating disorders mediated by dihydrotestosterone and reports no new clinical findings.

research Encapsulation of finasteride with native and modified γ-cyclodextrins. Extensive characterization of the complexes

8 citations , July 2020 in “International Journal of Pharmaceutics”

In this study, complexation with cyclodextrins was reported to increase the solubility of FIN for potential use in aqueous formulations for treating male androgenic alopecia.

research In vivo and in silico evaluation of the ameliorative effect of hesperidin on finasteride-induced testicular oxidative stress in Wistar rats

4 citations , October 2020 in “Toxicology Mechanisms and Methods”

This study found that in male rats, hesperidin co-administration ameliorated finasteride-induced testicular toxicity by reducing oxidative stress and improving antioxidant status, sperm parameters, and enzyme activity compared to finasteride treatment alone.

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