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research Dendritic polyglycerol and N-isopropylacrylamide based thermoresponsive nanogels as smart carriers for controlled delivery of drugs through the hair follicle

62 citations , November 2016 in “Nanoscale”

In this study, researchers developed thermoresponsive nanogels that effectively penetrate hair follicles and release a model drug when triggered by temperature, demonstrating greater penetration for medium to large nanogels (300–500 nm) compared to smaller ones.

research Potential Multi‐Functional Sprayable Poly(N‐Isopropylacrylamide)/Dextran Hydrogel Dressings With Incorporation of Silver Nanowires

3 citations , May 2025 in “Journal of Applied Polymer Science”

This study developed a multifunctional, sprayable hydrogel with temperature responsiveness, showing strong antimicrobial properties against E. coli and S. aureus, antioxidant activity, and cytocompatibility, indicating potential for wound healing applications.

research Incorporating redox-sensitive nanogels into bioabsorbable nanofibrous membrane to acquire ROS-balance capacity for skin regeneration

60 citations , March 2021 in “Bioactive Materials”

This study found that nanofibrous membranes containing PNA nanogels enhanced wound healing in mice by modulating reactive oxygen species levels, improving cell adhesion and proliferation.

research Bioinspired tuning of glycol chitosan for 3D cell culture

61 citations , September 2016 in “NPG Asia Materials”

This study developed thermo-reversible glycol chitosan hydrogels that effectively form and maintain 3D cell spheroids within one day, offering a simplified method for creating biologically realistic cultures for tissue regeneration and drug screening applications.

research Noyes-Whitney Dissolution Model-Based pH-Sensitive Slow Release of Paclitaxel (Taxol) from Human Hair-Derived Keratin Microparticle Carriers

9 citations , January 2021 in “BioMed research international”

This study describes a method to extract and characterize keratin particles from human hair, finding they can encapsulate the anticancer drug Paclitaxel with significant efficiency, releasing it in a pH-dependent manner potentially beneficial for targeted cancer treatment.

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community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

26 upvotes 4 years ago

N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.

community Clinical Trial: N-Acetyl-Cysteine for Treatment of AGA in Men

5 upvotes 5 years ago

N-Acetyl-Cysteine (NAC) is being explored for treating hair loss, but users report mixed results. Some also mention using Quercetin and Resveratrol without significant hair improvement.

community Minokem-N cotains hydrocortisone?

2 upvotes 1 year ago

Minokem-N's composition is unclear, with concerns about unlisted hydrocortisone. Users discuss alternatives like AloATM, which lacks soothing agents, and the challenges of verifying ingredients.

community What's the deal with Spectral.DNC-N/'nanoxidil'?

4 upvotes 4 years ago

Nanoxidil is considered to have better absorption and fewer side effects than minoxidil, with added DHT blockers. The user is questioning if switching to the more expensive Spectral.DNC-N is worthwhile compared to cheaper options like Kirkland minoxidil.

community Has anyone here tried Vichy Dercos Aminexil Clinical R.E.G.E.N. Booster?

in Technology 1 upvotes 6 months ago

The conversation discusses the effectiveness of Vichy Dercos Aminexil Clinical R.E.G.E.N. Booster for hair shedding and thinning. The main ingredient, Aminexil, is compared to Minoxidil, and the user seeks real experiences to determine its efficacy.

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