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5 / 15 resultslearn Dutasteride
Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn Minoxidil
An essential vasodilator with some anti-androgenic effects, has excellent safety record
learn Overview
Research
5 / 1000+ resultsresearch Comparison of Polynucleotide and Polydeoxyribonucleotide in Dermatology: Molecular Mechanisms and Clinical Perspectives
PN hydrates skin; PDRN heals and regenerates skin and hair.
research Novel Anti-Melanogenesis Properties of Polydeoxyribonucleotide, a Popular Wound Healing Booster
Polydeoxyribonucleotide (PDRN) may help lighten skin and treat hyperpigmentation.
research An Evaluation of Collagen Peptide for Transdermal Delivery Using Strat-M Membrane and Excised Mouse Skin
Strat-M® membrane can effectively replace mouse skin for testing collagen peptide delivery.
research Hair Growth-Promoting Effects of Sargassum Glaucescens Oligosaccharides Extracts
Extracts from a type of brown seaweed can help promote hair growth.
research Iron Plays a Certain Role in Patterned Hair Loss
Iron deficiency may contribute to hair loss.
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community FCE 28260: A Forgotten 5α-Reductase Inhibitor
by
nkrata
in Research
330 upvotes
1 year ago FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community Dutasteride Mesotherapy seems like the best of all worlds.. Why isn't it talked about more?
Dutasteride mesotherapy is discussed as a potentially effective hair loss treatment with no sexual side effects, requiring less frequent application than daily pills. However, it is not widely popular due to limited availability, high cost, and skepticism about its effectiveness.
community Why nobody uses 0.25% (2.5mg/ml)?
The conversation is about the effectiveness of 0.25% topical finasteride compared to other concentrations and forms. Users discuss its potential for better scalp DHT reduction and fewer side effects, with some preferring topical over oral treatments.
community Has been on minoxidil for 5 years. Microneedling for 4 weeks no results.
The user has used minoxidil for five years and added microneedling for four weeks without seeing results. They are considering a hair transplant but are advised that hair loss will persist without a DHT blocker.
community Topical Fin Vs Oral Fin. Which is better and has less sides?
Comparing the effectiveness and side effects of topical finasteride versus oral finasteride, with people sharing their experiences using both treatments to manage hair loss.