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GlossaryMerkel cells

specialized skin cells that detect touch and pressure

Merkel cells are specialized skin cells located in the epidermis, particularly in areas with high tactile sensitivity like fingertips. They function as mechanoreceptors, meaning they help detect touch and pressure, and are connected to nerve endings to transmit sensory information to the brain.

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research Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection

133 citations, May 2016 in “Cell Host & Microbe”

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

research The Cellular Basis of Mechanosensory Merkel-Cell Innervation During Development

32 citations, February 2019 in “eLife”

BMP signaling is essential for the development of touch domes.

research Spatial Relationship Between Merkel Cells and Langerhans Cells in Human Hair Follicles

27 citations, December 2002 in “Journal of dermatological science”

Merkel cells and Langerhans cells in hair follicles are closely connected and may interact.

Multifunctional Merkel Cells: Their Roles in Electromagnetic Reception, Fingerprint Formation, Reiki, Epigenetic Inheritance, and Hair Form

research Multifunctional Merkel Cells: Their Roles in Electromagnetic Reception, Fingerprint Formation, Reiki, Epigenetic Inheritance, and Hair Form

23 citations, March 2010 in “Medical hypotheses”

Merkel cells may have roles in sensing magnetic fields, creating fingerprints, Reiki energy healing, passing on environmental information to offspring, and influencing hair shape.

research Direct Cellular Reprogramming Enables Development of Viral T Antigen-Driven Merkel Cell Carcinoma in Mice

14 citations, February 2022 in “The Journal of clinical investigation/The journal of clinical investigation”

Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.

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