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    Glossary Mast Cell

    Mast cells are a type of white blood cell that play a crucial role in the immune system, particularly in allergic reactions and inflammation. In the context of hair loss, mast cells are relevant due to their involvement in the inflammatory processes that can affect hair follicles, potentially leading to conditions such as alopecia areata. Key distinguishing characteristics of mast cells include their large granules filled with histamine and other mediators, which can influence blood flow and immune responses in the skin and hair follicles. Their activation and degranulation can contribute to the disruption of normal hair growth cycles.

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    1. Endocannabinoids limit excessive mast cell maturation and activation in human skin Journal of Allergy and Clinical Immunology · 2012 · 124 citations
    2. Stress exposure modulates peptidergic innervation and degranulates mast cells in murine skin Brain Behavior and Immunity · 2004 · 115 citations
    3. A simple immunofluorescence technique for simultaneous visualization of mast cells and nerve fibers reveals selectivity and hair cycle - dependent changes in mast cell - nerve fiber contacts in murine skin Archives of Dermatological Research · 1997 · 109 citations
    4. Mast cell deficient and neurokinin-1 receptor knockout mice are protected from stress-induced hair growth inhibition Journal of Molecular Medicine · 2005 · 76 citations
    5. A Review of the Evidence for and against a Role for Mast Cells in Cutaneous Scarring and Fibrosis International Journal of Molecular Sciences · 2020 · 35 citations
    6. Dermal fibrosis in male pattern hair loss: a suggestive implication of mast cells Archives of Dermatological Research · 2008 · 19 citations
    7. The Pathological Changes and Polymorphonuclear and Mast Cell Responses in the Skin of Specific Pathogen‐free Lambs Following Primary and Secondary Challenge with Orf Virus Veterinary Dermatology · 1990 · 18 citations
    8. <i>Urticaria Neonatorum:</i> Accumulation of tryptase‐expressing mast cells in the skin lesions of newborns with Erythema Toxicum Pediatric allergy and immunology · 2007 · 14 citations
    9. Acute Stress-Induced Changes in Follicular Dermal Papilla Cells and Mobilization of Mast Cells: Implications for Hair Growth Annals of Dermatology · 2016 · 13 citations
    10. Presence of mast cells and mast cell degranulation in scalp biopsies of telogen effluvium International Journal of Trichology · 2017 · 9 citations
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