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Research

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research Acne: a side‐effect of masculinizing hormonal therapy in transgender patients

57 citations , August 2018 in “British Journal of Dermatology”

This review discusses the pathogenesis and treatment of acne in transgender men on testosterone therapy and reports no new clinical results, emphasizing the need for tailored guidelines.

research Incidence and Factors Associated With Androgenetic Alopecia Among Transgender and Gender-Diverse Patients Treated With Masculinizing Hormone Therapy

3 citations , February 2021 in “JAMA Dermatology”

Masculinizing hormone therapy increases the risk of hair loss in transgender and gender-diverse patients.

Acne, Androgenetic Alopecia, and Atopic Dermatitis in Transgender Patients on Hormone Therapy: A Retrospective Comparative Cohort Study

research 319 Acne, androgenetic alopecia, and atopic dermatitis in transgender patients on hormone therapy: A retrospective comparative cohort study

April 2021 in “Journal of Investigative Dermatology”

This study found that transgender patients on masculinizing hormone therapy had a higher likelihood of developing acne compared to cisgender women, and were more likely to experience AGA compared to cisgender women.

research What is the Rationale for Androgen Therapy for Women?

20 citations , January 2003 in “Treatments in Endocrinology”

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Changes in Kidney Hemodynamics During Gender-Affirming Hormone Therapy in Transgender Individuals - Findings from the KNIGHT Pilot Study

research 8483 Changes in kidney hemodynamics during gender-affirming hormone therapy in transgender individuals - findings from the KNIGHT pilot study

October 2024 in “Journal of the Endocrine Society”

This study found that feminizing hormone therapy increased GFR in transgender individuals assigned male at birth, suggesting an effect of sex hormones on kidney hemodynamics, while masculinizing therapy showed a slight, nonsignificant decrease in GFR.

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Community Join

5 / 14 results

community A little more than a month using red light therapy. I'm surprised by the progress.

263 upvotes 5 months ago

Red light therapy has shown promising results in hair regrowth for the user, who avoids minoxidil and finasteride due to side effects. The user follows a healthy lifestyle with diet, exercise, and sauna use, and will continue monitoring the therapy's effectiveness.

community My 2 Years Progress (Hair Recovery)

1465 upvotes 5 months ago

A person shared their hair regrowth journey using HIMS topical treatments with finasteride, minoxidil, hormone replacement therapy (HRT), and microneedling. They also discussed their transition as a transgender woman and the positive impact of HRT on hair recovery.

community Scarring Alopecia and NSAIDs?

4 upvotes 5 years ago

The user suspects scarring alopecia and is exploring NSAIDs and turmeric/pepper for inflammation-related hair loss, having experienced burning and thinning with finasteride and testosterone reduction. They are seeking feedback while unable to afford a dermatologist.

community I understand this topic has been discussed countless times, but hair loss is the most brutal experience for men.

in Chat 343 upvotes 1 year ago

Hair loss significantly affects men's confidence and mental health. Common treatments include finasteride, dutasteride, and minoxidil, with some considering hair transplants.

community 100 Day Progress & Managing Realistic Expectations (FTM 24)

99 upvotes 9 months ago

A trans man experiencing hair loss after starting testosterone treatment has seen positive results using topical minoxidil and finasteride, though his hair remains thin. He is considering continuing his current treatment and exploring additional options like microneedling and Breezula, while acknowledging the impact of testosterone on hair loss.

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Learn

4 / 801 results

learn Clascoterone

a novel topical treatment that inhibits DHT on androgen receptors

Can I use clascoterone if I'm undergoing gender-affirming hormone therapy? No published clinical trial has tested clascoterone in people on gender-affirming hormone therapy, so its safety in that group is unknown. The FDA label reports low systemic exposure and no described effect on blood testosterone, but it also records HPA-axis suppression and raised potassium in a small minority of subjects.

learn Spironolactone

powerful topical and oral anti-androgen used mostly by women

learn Pyrilutamide

highly targeted anti-androgen that might have minimal systemic effects

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

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Clinics

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