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Did you mean p38 MAP kinase?

Glossaryp38 MAPK (p38 MAP kinase)

enzyme involved in cellular stress and inflammation responses

p38 MAPK, or p38 mitogen-activated protein kinase, is an enzyme that plays a crucial role in cellular responses to stress and inflammation. It is part of a signaling pathway that helps cells react to various external stimuli, such as UV radiation, heat shock, and cytokines, by regulating the expression of specific genes involved in inflammation, cell differentiation, and apoptosis (programmed cell death). This pathway is significant in various biological processes and diseases, including cancer, cardiovascular diseases, and inflammatory conditions.

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Retinoid-Mediated Stimulation of Steroid Sulfatase Activity in Myeloid Leukemic Cell Lines Requires RARα and RXR and Involves the Phosphoinositide 3-Kinase and ERK-MAP Kinase Pathways

research Retinoid-Mediated Stimulation of Steroid Sulfatase Activity in Myeloid Leukemic Cell Lines Requires RARα and RXR and Involves the Phosphoinositide 3-Kinase and ERK-MAP Kinase Pathways

24 citations, September 2005 in “Journal of Cellular Biochemistry”

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

research Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection

133 citations, May 2016 in “Cell Host & Microbe”

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

research Metabolic Teamwork in the Stem Cell Niche

14 citations, May 2017 in “Cell metabolism”

Paneth cells and intestinal stem cells work together metabolically for stem cell function and regeneration.

research Recent Advances in Exosomal Non-Coding RNA-Based Therapeutic Approaches for Photoaging

3 citations, September 2023 in “Skin research and technology”

New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.

research Lentiviral Arrays for Live-Cell Dynamic Monitoring of Gene and Pathway Activity During Stem Cell Differentiation

13 citations, June 2014 in “Molecular therapy”

The lentiviral array can monitor and predict gene activity during stem cell differentiation.

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community 📈 Solving for very low dose topical finasteride titration intervals

in Research/Science 30 upvotes 3 months ago

The conversation discusses using very low dose topical finasteride to achieve specific serum DHT reduction percentages. It concludes that finasteride dosage increases linearly between 5-30% DHT reduction but requires exponential increases for reductions up to 70%.

community What ever happened to hairlosshelp.com ??!

in Update 35 upvotes 2 years ago

User began losing hair in 2006, used Avodart and got a hair transplant in 2012. They discuss the decline of hair loss forums and the shift to Reddit, which isn't ideal for long-form discussions.

community Am I in a long second shed from treatment or is this my regular hair loss

in Treatment 5 upvotes 8 months ago

The user has been using Minoxidil, Ketoconazole shampoo, and a dermastamp for 7 months and experienced a period with no shedding, but is now shedding about 100 hairs a day and is questioning if this is a result of the treatment or their normal hair loss. They are unable to start finasteride and are considering stopping the treatment due to the shedding.

community Topical Saw Palmetto: An Alternative to Microdosing Topical Finasteride?

in Product 16 upvotes 1 year ago

The user is exploring topical Saw Palmetto as a milder alternative to microdosing topical Finasteride for hair loss, aiming to minimize systemic DHT impact. They plan to experiment with this herbal remedy for a year to assess its effectiveness on their mild androgenetic alopecia without significant side effects.

community AnagenInc says GT20029 is possible now

in Research/Science 116 upvotes 1 year ago

AnagenInc is ready to produce a hair loss treatment called GT20029 if there is enough demand. People are discussing combining it with other treatments like finasteride and minoxidil, and some are concerned about the legitimacy and safety of gray market products.

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