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a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
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learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn Dutasteride
Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
learn GT20029
research compound made to degrade androgen receptors in scalp
Research
5 / 1000+ resultsresearch Live-Imaging the Interface Between Homeostasis and Cancer Initiation
Mutant cells in hair follicles are influenced by their location and interactions with surrounding cells.
research Incidence of Liver Toxicity Associated with the Use of Flutamide in Prostate Cancer Patients
Flutamide rarely causes liver toxicity in prostate cancer patients.
research Cronkhite-Canada Syndrome Associated with Colon Cancer Metastatic to Liver
A patient with Cronkhite-Canada Syndrome developed colon cancer that spread to the liver, showing the need for regular cancer checks in such patients.
research Glycyrrhetinic Acid Functionalized Nanoparticles for Drug Delivery to Liver Cancer
Licorice root-derived nanoparticles target liver cancer cells to improve treatment and reduce side effects.
research Hsa_circ_0002980 Prevents Proliferation, Migration, Invasion, and Epithelial-Mesenchymal Transition of Liver Cancer Cells Through MicroRNA-1303/Cell Adhesion Molecule 2 Axis
hsa_circ_0002980 can help stop liver cancer cells from growing and spreading.
Community Join
5 / 1000+ resultscommunity Sensitive liver, topical fin safe to try?
Topical finasteride is considered safer for the liver than oral finasteride due to less systemic absorption, but regular liver function tests are advised. The user is concerned about liver health due to a history of NAFLD and is exploring topical finasteride as a safer alternative.
community Will my liver get destroyed long term on this stack ??
A user is considering a long-term hair loss treatment stack including Dutasteride, Finasteride, and oral Minoxidil, and is concerned about potential liver damage. Some responses suggest the stack is excessive, while others believe it's not harmful to the liver, but recommend regular blood work to monitor health.
community Nutrafol backed by Science to reverse male balding?
Nutrafol helps improve hair thickness and hairline but may have potential health risks like liver damage and increased prostate cancer risk. The user plans to continue Nutrafol at a lower dosage while managing seborrheic dermatitis and considers future use of topical finasteride, minoxidil, rosemary oil, and microneedling.
community Would Salicylic Acid shampoo hinder Oral Minoxidil? Like topical?
Salicylic Acid shampoo may hinder topical minoxidil but not oral minoxidil, which works through the liver. The user plans to continue using oral minoxidil and is concerned about the shampoo's effect on it.
community 5ARI (dutasteride) Associated with Adverse Metabolic Effects
Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.