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research hsa_circ_0002980 prevents proliferation, migration, invasion, and epithelial-mesenchymal transition of liver cancer cells through microRNA-1303/cell adhesion molecule 2 axis

3 citations , December 2023 in “Aging”

In liver cancer cells, this study found that upregulating hsa_circ_0002980 inhibits cell proliferation, metastasis, and EMT by modulating the miR-1303/CADM2 axis, suggesting it as a potential therapeutic target.

research Abstract 4385: Live-imaging the interface between homeostasis and cancer initiation

July 2016 in “Cancer research”

This study found that mutant cells in hair follicles can be tolerated or eliminated by surrounding normal tissue, suggesting the potential for wild-type cells to counteract oncogenic mutations.

research Incidence of liver toxicity associated with the use of flutamide in prostate cancer patients

116 citations , May 1992 in “The American Journal of Medicine”

This study found that flutamide-induced liver toxicity in prostate cancer patients was very rare, occurring in only 0.18% of cases with clinical manifestations, and symptoms resolved after discontinuing the drug.

research Cronkhite-Canada syndrome associated with colon cancer metastatic to liver

5 citations , September 2017 in “Medicine”

In this case report, a patient with Cronkhite-Canada Syndrome developed colon cancer and liver metastasis despite hormone therapy, highlighting the need for regular monitoring and early detection strategies.

research Glycyrrhetinic Acid Functionalized Nanoparticles for Drug Delivery to Liver Cancer

31 citations , August 2018 in “Journal of biomedical nanotechnology”

This review highlights GA-mediated nanoparticles for liver-targeting drug delivery in liver cancer treatment and reports no new clinical results.

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community liver problem from finasteride/dutasteride

13 upvotes 3 years ago

The conversation discusses liver issues potentially linked to long-term use of finasteride and dutasteride, with users sharing similar experiences of elevated liver enzymes, high cholesterol, and other health concerns. The consensus suggests stopping the medication and consulting a healthcare professional for proper diagnosis and treatment.

community Sensitive liver, topical fin safe to try?

in Finasteride 98 upvotes 1 year ago

Topical finasteride is considered safer for the liver than oral finasteride due to less systemic absorption, but regular liver function tests are advised. The user is concerned about liver health due to a history of NAFLD and is exploring topical finasteride as a safer alternative.

community Deciding Between Oral or Topical Min and Fin with Fatty Liver

in Basic Questions 77 upvotes 3 months ago

The user is experiencing hair loss and is considering using topical minoxidil and finasteride due to concerns about liver health, specifically elevated ALT levels from fatty liver. They are advised to start with topical treatments while continuing weight loss and dietary changes to improve liver function.

community Nutrafol backed by Science to reverse male balding?

in Research/Science 1 upvotes 1 year ago

Nutrafol helps improve hair thickness and hairline but may have potential health risks like liver damage and increased prostate cancer risk. The user plans to continue Nutrafol at a lower dosage while managing seborrheic dermatitis and considers future use of topical finasteride, minoxidil, rosemary oil, and microneedling.

community Would Salicylic Acid shampoo hinder Oral Minoxidil? Like topical?

in Research/Science 3 upvotes 2 years ago

Salicylic Acid shampoo may hinder topical minoxidil but not oral minoxidil, which works through the liver. The user plans to continue using oral minoxidil and is concerned about the shampoo's effect on it.

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