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GlossaryHepatocellular Carcinoma (Liver Cancer)

most common type of primary liver cancer, often called HCC

Hepatocellular Carcinoma (HCC) is the most common type of primary liver cancer, originating from the main type of liver cells called hepatocytes. It often develops in the context of chronic liver diseases such as cirrhosis or hepatitis B and C infections, and it can lead to symptoms like abdominal pain, weight loss, and jaundice.

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community Attention Finasteride / Dutasteride and Your liver

in Finasteride/Dutasteride 373 upvotes 1 month ago

Finasteride may cause elevated liver enzymes, potentially leading to liver issues, though this is rare. Users should monitor liver function and consider topical alternatives if liver sensitivity occurs.

community Pyrilutamide is literally my only hope

in Chat 91 upvotes 2 years ago

Considering treatments for hair loss, including Minoxidil, Finasteride, RU58841, Fluridil and Pyrilutamide. The user is weighing the risks of taking unapproved medication before it has been mass produced.

community Progress: 3 months min 4 times a week/dermaroll twice a week/antigray shampoo

in Is this regrowth? 126 upvotes 1 year ago

The post discusses hair regrowth progress after 3 months of using Minoxidil four times a week, dermarolling twice a week, and using an anti-gray shampoo. The conversation includes speculation about the effectiveness of the shampoo, with some users noting visible darkening and growth of hair.

community Next month marks 2 years on Dutasteride. When does it start working?

in Finasteride/Dutasteride 36 upvotes 6 months ago

A user has been on dutasteride for nearly 2 years with no improvement in hair loss, expressing frustration. Other users suggest checking for other health conditions, getting bloodwork, and considering stopping TRT or trying finasteride.

community PSA: My GP told me you should get yearly kidney and liver tests if you are on Dutasteride

in Update 15 upvotes 5 months ago

Dutasteride users should get yearly kidney and liver tests, especially young people. General health checkups are not common in the UK, but such tests are recommended as a precaution.

community Will my liver get destroyed long term on this stack ??

in Chat 15 upvotes 10 months ago

A user is considering a long-term hair loss treatment stack including Dutasteride, Finasteride, and oral Minoxidil, and is concerned about potential liver damage. Some responses suggest the stack is excessive, while others believe it's not harmful to the liver, but recommend regular blood work to monitor health.

community Is this true? Is long term taking fin harmful to the liver?

in Chat 127 upvotes 11 months ago

The conversation discusses whether long-term use of finasteride (Fin) is harmful to the liver, with various opinions on side effects and comparisons to other substances. Specific treatments mentioned include finasteride, minoxidil (Min), and RU58841 (RU).

community Can somebody tell my why Scube3 is not going to work?

in Research/Science 8 upvotes 6 months ago

The conversation discusses concerns about Scube3's effectiveness and potential cancer link. It questions whether Scube3 can regrow hair and how well it works according to researchers.

community What are these spots on my scalp

in Treatment 51 upvotes 5 months ago

A user noticed non-itchy, non-bleeding spots on their scalp while experiencing hair loss. Replies suggest the spots are likely sunspots or liver spots and recommend seeing a dermatologist; hair loss is attributed to male pattern baldness.

community A warning to those thinking about using Dutasteride

in Finasteride/Dutasteride 99 upvotes 4 years ago

The potential risks of long-term use of Dutasteride and how it may be linked to elevated liver enzymes, cholesterol levels, and decreased testosterone. Alternative treatments such as Finasteride and RU58841 were also discussed.

community 5ARI (dutasteride) Associated with Adverse Metabolic Effects

23 upvotes 6 years ago

Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.

community Having androgen receptor density and sensitivity at wrong f*ing place

in Satire 7 upvotes 2 months ago

The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

community I find it crazy how some people like this bloke have 0 DHT sensitivity. He is on grams of anabolic steroids and has a full, thick head of hair. I wish all of on here had this guys hair genes lol

in Satire 443 upvotes 1 year ago

The conversation is about hair loss and the possibility of maintaining a full head of hair while using anabolic steroids. Some users believe that having good hair genes and taking hair loss protocols can help prevent hair loss while on steroids.

community Wtf have we been doing for the last 30 years

in Treatment 525 upvotes 4 days ago

Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

community Anyone else got a folder on their phone full of scalp shots 😂

in Satire 635 upvotes 8 months ago

People are sharing their experiences of keeping a hidden folder on their phones with photos documenting their hair loss. Some users discuss the emotional impact, while one mentions using dutasteride and oral minoxidil without noticeable change.

community Male pattern baldness, and mental health

in Finasteride/Dutasteride 331 upvotes 10 months ago

A 48-year-old man has been using minoxidil for 15 years and considered finasteride but stopped due to potential side effects. He is concerned about his mental health and the impact of hair loss on self-image, and he encourages support among men experiencing hair loss.

community Whats this thing on my scalp I tried killing it for over a year with salicylic acid and freeze off but it doesn’t help. Could this thing affect my follicles ? My hairloss started when this thing grew and minoxidil and fin haven’t been doing anything any other treatments?

in Minoxidil 32 upvotes 2 years ago

A user's scalp issue that may be causing their hair loss and potential treatments, such as salicylic acid, finasteride, minoxidil, ketoconazole shampoo, and visiting a dermatologist.

community Spironolactone for hair loss??

in Product 6 upvotes 2 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, and Spironolactone. One user shares success with Finasteride, Minoxidil, and low-dose Cyproterone Acetate, but warns against long-term use of oral anti-androgens.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 2 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Dutasteride takes 1-3 months to work in the scalp. Not weeks. Be careful.

in Finasteride/Dutasteride 41 upvotes 4 months ago

Dutasteride takes 1-3 months to affect scalp DHT levels, not just a week. The prostate absorbs Dutasteride faster than the scalp due to different vascular networks and enzyme densities.

community Approximately 1 month on oral dut+ oral min

in Progress Pictures 103 upvotes 6 months ago

A user shared progress pictures after one month on oral dutasteride and minoxidil, noting some improvement despite initial shedding. They previously used finasteride for a year without noticeable change and emphasized the importance of photo comparisons.

community Why isn't anybody on topical bicalutamide?

in Research/Science 2 upvotes 6 months ago

Topical bicalutamide is discussed as a potential hair loss treatment. Other treatments mentioned include Minoxidil, finasteride, and RU58841.

community NootBro Recommendations… How Do We Feel

in Research/Science 9 upvotes 6 months ago

The conversation is about hair loss treatments, specifically a stack including topical Ashwagandha, Copper Peptide, Gotu Kola, Ketoconazole, and PDA. One user found Topical and Sub-Q GHK-CU effective.

community I bought a microscope, how does my scalp/hairs look? I've been suffering diffuse thinning and hair loss after covid and never recovered (2 yrs ago) I eat healthy, in shape and workout.

in Progress Pictures 86 upvotes 9 months ago

A person with hair loss since COVID-19 is considering treatments like finasteride and minoxidil but is hesitant due to potential side effects. Suggestions include visiting a dermatologist, using a ketoconazole shampoo, and considering that post-COVID hair loss might be an autoimmune response.

community I have been applying undiluted, pure 100% peppermint oil to my scalp, 2.5ml a day as an experiment

in Treatment 86 upvotes 1 year ago

A user is experimenting with applying undiluted peppermint oil to their scalp daily to stimulate hair growth, based on a rat study where peppermint oil outperformed minoxidil. The user reports immediate hair thickening and increased scalp blood flow, while others in the conversation express skepticism, humor, and concern about the undiluted application.

community Finasteride/dut. causes NAFLD,IR,diabetes,kidney dysfunction is it correct.

in Finasteride/Dutasteride 139 upvotes 1 year ago

Hair loss discussion mentions treatments like Finasteride, Dutasteride, and Minoxidil. Users share experiences, side effects, and advice on using these treatments.

community Tips/Advice on current situation aside from shaving bald

in Progress Pictures 1 upvotes 3 years ago

The user experienced worse hair after removing a wig system and has been using Hairband 82 Comfort Flex, Hair Max supplements, dermarolling, and a scalp massager for 4 months without clear results. They are hesitant to use Minoxidil due to shedding concerns and avoid finasteride due to side effects, preferring Saw Palmetto instead.

community What's your experience with using hinoki tree oil and/or procyanidin b2?

in Treatment 6 upvotes 3 years ago

Hair loss discussion includes treatments like hinoki tree oil and procyanidin b2. Experiences and effectiveness of these treatments are shared.

community Would Fluridil and Alfatradiol work effectively in conjunction with each other?

in Treatment 10 upvotes 4 years ago

Whether using both Fluridil and Alfatradiol together could be more effective than either one alone as a hair loss treatment, given their different mechanisms of action.

community Fluridil downregulates androgen receptor expression?

in Research/Science 1 upvotes 11 months ago

Fluridil may decrease the number of androgen receptors in hair follicles by up to 95%. This suggests a different action mechanism from other non-steroidal antiandrogens like RU58841, indicating they might be used together.