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GlossaryCirrhosis

chronic liver disease marked by scarring and impaired function

Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, is a chronic liver disease characterized by the replacement of healthy liver tissue with scar tissue, leading to impaired liver function. This condition can result from various causes, including chronic alcohol abuse, hepatitis infections, and non-alcoholic fatty liver disease, and it can lead to complications such as liver failure, portal hypertension, and increased risk of liver cancer.

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Single Nucleotide Polymorphisms Associated with Elevated Alanine Aminotransferase in Patients Receiving Asunaprevir Plus Daclatasvir Combination Therapy for Chronic Hepatitis C

research Single Nucleotide Polymorphisms Associated with Elevated Alanine Aminotransferase in Patients Receiving Asunaprevir Plus Daclatasvir Combination Therapy for Chronic Hepatitis C

2 citations , July 2019 in “PLOS ONE”

Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.

research The Myth of Beneficent Nature: The Risks of Herbal Preparations

165 citations , July 1992 in “Annals of Internal Medicine”

Herbal products can be dangerous and cause serious health issues.

research High Circulating Estrone and Low Testosterone Correlate with Adverse Clinical Outcomes in Men with Advanced Liver Disease

17 citations , March 2016 in “Liver international”

Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.

Preponderance of Serum and Intra-Hepatic 5α-Dihydrotestosterone in Males with Hepatocellular Carcinoma Despite Low Circulating Androgen Levels

research Preponderance of Serum and Intra-Hepatic 5α-Dihydrotestosterone in Males with Hepatocellular Carcinoma Despite Low Circulating Androgen Levels

8 citations , January 1986 in “Journal of hepatology”

Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.

research Commonly Encountered Symptoms and Their Management in Patients With Cirrhosis

November 2024 in “Frontiers in Medicine”

Cirrhosis affects quality of life with various symptoms, requiring a holistic, multidisciplinary approach for management.

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community How much would a high dose dutasteride scalp dht inhibition be?

in Finasteride/Dutasteride 10 upvotes 1 year ago

The conversation discusses the potential for high doses of dutasteride to completely inhibit scalp DHT and speculates whether this could cure baldness when combined with a topical antiandrogen. Specific dosages mentioned are 0.5 mg reducing scalp DHT by 55% and 2.5 mg by about 79%.

community HAHAHAHHAHA WTF DUDE I CAN’t even escape hairloss for like an hour , just hoped on league to witness this , btw “Finasteride 5mg”totally carried the game i hope the actual drug carries us too.😂

in Chat 829 upvotes 2 years ago

The conversation jokes about hair loss treatments, mentioning finasteride, minoxidil, dutasteride, microneedling, ketoconazole shampoo, and rosemary oil as if they were players in a game. Some users also discuss the use of finasteride for prostate issues and the possibility of splitting the dose.

community Imo everyone should take serrapeptase for a short extended period to break up scar tissue in their scalp

in Research/Science 2 years ago

Treatments for hair loss, such as Minoxidil, Finasteride and RU58841, as well as using serrapeptase to break up scar tissue in the scalp.

community Who won’t respond to minoxidil? (Studies)

in Research/Science 32 upvotes 1 week ago

Minoxidil's effectiveness varies due to differences in sulfotransferase enzyme levels in the scalp, affecting people with conditions like ASD, liver disease, and androgenic alopecia. Treatments like topical tretinoin, microneedling, and using minoxidil sulfate instead of regular minoxidil can improve results for those with low enzyme levels.

community Attention Finasteride / Dutasteride and Your liver

in Finasteride/Dutasteride 380 upvotes 1 year ago

Finasteride may cause elevated liver enzymes, potentially leading to liver issues, though this is rare. Users should monitor liver function and consider topical alternatives if liver sensitivity occurs.

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