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GlossaryLgr5 (Leucine-rich repeat-containing G-protein coupled receptor 5)

protein marker for adult stem cells in hair follicles

Lgr5, or Leucine-rich repeat-containing G-protein coupled receptor 5, is a protein that serves as a marker for adult stem cells in various tissues, including hair follicles. It plays a crucial role in the regeneration and repair of these tissues, making it significant in studies related to hair growth and alopecia.

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research Constitutive Internalization of the Leucine-Rich G Protein-Coupled Receptor-5 (LGR5) to the Trans-Golgi Network

58 citations , February 2013 in “Journal of Biological Chemistry”

LGR5 mainly stays inside cells, moving to the trans-Golgi network, and this process is important for its role in cell signaling.

research Transient Calcium Entry by Plasmalogen-Mediated Activation of Receptor Potential Cation Channel Promotes AMPK Activity

3 citations , November 2022 in “Frontiers in molecular biosciences”

Plasmalogens activate a channel in cells that may stimulate hair growth.

research Treatment of Full-Thickness Skin Wounds with Blood-Derived CD34+ Precursor Cells Enhances Healing with Hair Follicle Regeneration

2 citations , May 2019 in “Advances in wound care”

Blood-derived CD34+ cells speed up healing, reduce scarring, and regrow hair in skin wounds.

research Stem Cell Plasticity Enables Hair Regeneration Following Lgr5+ Cell Loss

56 citations , May 2017 in “Nature Cell Biology”

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

research Expression of Signaling Components in Embryonic Eyelid Epithelium

5 citations , February 2014 in “PloS one”

Eyelid cells share signaling components but differ in pathway activity.

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community 30M Experiencing Shedding After Restarting Min + Fin + Mesotherapy, Is It Too Late?

in General 168 upvotes 1 month ago

A 30-year-old is seeking advice on hair loss treatment, currently using oral minoxidil, finasteride, mesotherapy, and a supplement. They are experiencing shedding and are anxious about the effectiveness of the treatment, asking if they should continue or consider other options like topicals or microneedling.

community Indian Subcontinent specific : Fin effects

in Finasteride/Dutasteride 4 upvotes 5 years ago

Oral finasteride is recommended over topical finasteride for men in the Indian subcontinent, with no reported side effects. Minoxidil and dermarolling are also suggested, while dietary supplements and topical finasteride are deemed less effective.

community Carnitine Tartrate + Potassium chloride + Niacin

9 upvotes 11 years ago

The post discusses using Carnitine Tartrate, Potassium Chloride, and Niacin to reduce hair shedding, with the user experiencing significant improvement. The user also suggests considering a ketogenic/paleo diet for those with insulin resistance-related hair loss.

community Is EAA good or bad for hair? I cant find Any information about it.

in Product 1 upvotes 4 years ago

The conversation is about whether an EAA supplement affects hair health. The user lists the ingredients but does not receive a definitive answer.