body's tissues are less responsive to vitamin D effects
Vitamin D Resistance, also known as Vitamin D Insensitivity, is a condition where the body's tissues are less responsive to the effects of vitamin D. This can result from genetic mutations affecting the vitamin D receptor (VDR) or other components of the vitamin D metabolic pathway, leading to issues like rickets, osteomalacia, or other bone and mineral disorders despite adequate levels of vitamin D in the blood.