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    Glossary Receptors

    specialized proteins that bind specific molecules to trigger cellular responses

    Receptors are specialized protein molecules found on the surface of cells or within cells that bind to specific substances, such as hormones, neurotransmitters, or drugs. When these substances attach to the receptors, they trigger a response within the cell, influencing various physiological processes. For example, in the context of hair biology, androgen receptors on hair follicle cells can bind to hormones like testosterone, affecting hair growth and potentially contributing to conditions like androgenetic alopecia (pattern baldness).

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    1. Clascoterone Topical androgen-receptor blocker, approved as an acne cream
    2. HMI-115 Experimental antibody that blocks the prolactin receptor
    3. GT20029 Experimental topical drug designed to break down androgen receptors
    4. Cyproterone a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
    5. Bicalutamide Nonsteroidal anti-androgen, originally a prostate cancer drug