18 citations
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May 1988 in “Journal of The American Academy of Dermatology” In this study, itraconazole was reported to effectively alleviate clinical symptoms in patients with recalcitrant Trichophyton rubrum infections, though toenail infections often recurred, indicating the need for further research on long-term efficacy and safety.
12 citations
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April 2005 in “Mycoses” This study found that 1-day itraconazole therapy was more effective for acute vulvovaginal candidosis than for recurrent cases, where relapses occurred despite no yeast resistance.
8 citations
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March 2018 in “Journal of Drug Delivery Science and Technology” This study found that treating paracoccidioidomycosis-infected mice with a nanoparticle formulation of itraconazole led to higher drug accumulation in lung, liver, and spleen tissues, improved treatment efficacy, and reduced side effects compared to traditional oral solutions.
3 citations
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November 2019 in “Journal of dermatology” This case report details the successful use of oral itraconazole in treating a giant tufted angioma with hair loss that developed during pregnancy, leading to significant symptom relief and hair regrowth after discontinuation of the medication.
3 citations
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December 1994 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” In this study, itraconazole was shown to accumulate in the deeper skin layers of guinea pigs after oral administration, suggesting this delivery method effectively targets infective organisms there.