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Glossary Isotretinoin

oral medication for severe acne unresponsive to other treatments

Isotretinoin, also known by brand names like Accutane, is a powerful oral medication primarily used to treat severe acne that hasn't responded to other treatments. It works by reducing the amount of oil released by oil glands in your skin, helping your skin renew itself more quickly. While highly effective, it can have significant side effects and is typically prescribed under strict medical supervision.

Research

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research Avaliação dos efeitos adversos clínicos e alterações laboratoriais em pacientes com acne vulgar tratados com isotretinoína oral

41 citations , June 2010 in “Anais Brasileiros de Dermatologia”

This study found that isotretinoin is a safe and well-tolerated acne treatment, with common adverse effects like cheilitis manageable through symptomatic medication and no significant changes in lipid or liver enzyme levels.

research Consensus on the use of oral isotretinoin in dermatology - Brazilian Society of Dermatology

22 citations , October 2020 in “Anais Brasileiros de Dermatologia”

This consensus concluded that oral isotretinoin is highly effective for treating acne and some off-label conditions, with common adverse events being manageable and rare serious risks not contraindicating use.

research Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin

8 citations , October 2021 in “The international journal of risk and safety in medicine”

This paper describes the development of diagnostic criteria for several enduring sexual dysfunction conditions following the use of certain medications, highlighting common sexual and non-sexual symptoms.

research UTILIZAÇÃO DE ISOTRETINOÍNA ORAL NO TRATAMENTO DA ALOPECIA FIBROSANTE FRONTAL: SÉRIE DE CASOS

September 2021 in “Revista Interdisciplinar em Saúde”

In this observational study, treatment with oral isotretinoin was reported to stabilize hair loss in patients with frontal fibrosing alopecia, offering potential guidance for clinicians on its therapeutic use, with implications for improving affected patients' self-esteem.

research Prevalência e fatores relacionados às reações adversas no tratamento da acne com isotretinoína

December 2024 in “Medicina (Ribeirão Preto)”

This study found that 83% of acne patients treated with isotretinoin experienced adverse reactions, with the number of reactions related to treatment duration rather than sex, age, or dosage.

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Community Join

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community Isotretinoin and Tretinoin difference

in Product 2 upvotes 1 year ago

Isotretinoin and tretinoin are different; isotretinoin can cause hair loss and has more side effects. Tretinoin may affect minoxidil absorption, and users suggest waiting before applying minoxidil.

community here is why isotretinoin might cause hair loss and maybe why dupa happens.

in Research/Science 7 upvotes 3 years ago

Isotretinoin may cause hair loss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hair loss.

community Does anyone here take isotretinoin to make their scalp less oily?

2 upvotes 5 months ago

The conversation discusses using isotretinoin (Accutane) to reduce scalp oiliness and manage scalp issues like seborrheic dermatitis, inflammation, and chronic itch. A user shares that taking 20mg of Accutane every other day effectively reduces oily hair and skin.

community can topical retinol ( vitamin A ) affect hair / hairloss ???

4 upvotes 3 years ago

Topical retinol does not affect hair loss and may help hair regrowth. It is different from isotretinoin, which can cause hair loss due to its systemic effects.

community DHT Itch and Oily Scalp Explained (and how to fix it)

90 upvotes 3 months ago

Malassezia overgrowth can worsen oily scalp and inflammation, contributing to hair loss. Treatments include antifungal shampoos, C6/C8 MCT oil, low-dose isotretinoin, finasteride, and dutasteride.

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