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GlossaryCD123 (Interleukin-3 receptor subunit alpha)

protein receptor on some immune and cancer cells

CD123 is a protein found on the surface of certain cells, including some immune cells and cancer cells. It acts as a receptor for a molecule called interleukin-3 (IL-3), which is involved in cell growth and differentiation. In medical research and treatment, CD123 is often targeted in therapies for certain types of leukemia and other blood disorders.

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research The JAK/STAT Signaling Pathway: From Bench to Clinic

489 citations, November 2021 in “Signal Transduction and Targeted Therapy”

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

research Characterization of CD4+ Stem Cells of the Skin and Their Role in Skin Homeostasis and Tumorigenesis

1 citations, January 2021

CD4+ skin cells may be precursors to basal cell carcinoma.

research Updates in the Pathogenesis of Alopecia Areata

April 2021 in “Sohag Medical Journal”

Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.

research Cannabinoid Signaling in the Skin: Therapeutic Potential of the Cutaneous Cannabinoid System

142 citations, March 2019 in “Molecules/Molecules online/Molecules annual”

Cannabinoids may help treat various skin conditions.

research Risk Factors for Prostate Cancer: An Umbrella Review of Prospective Observational Studies and Mendelian Randomization Analyses

March 2024 in “PLoS medicine”

Physical activity, height, and smoking affect prostate cancer risk.

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community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 5 months ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.