22 citations
,
January 2014 in “Journal of Interferon & Cytokine Research”
In this study, researchers found that specific IL18 genetic variants may be linked to increased susceptibility to alopecia areata in a Korean population.
12 citations
,
January 2018 in “Journal of Clinical Laboratory Analysis”
This study found that IL-18 rs187238 and rs1946518 single nucleotide polymorphisms were associated with increased susceptibility to alopecia areata in a Turkish population.
In this case-control study, researchers found that patients with alopecia areata had significantly higher serum levels of interleukin-18 and NLRP3 compared to healthy controls, suggesting a potential link between these inflammatory markers and the disease.
7 citations
,
February 2023 in “Inflammation and Regeneration”
This study found that IL-1α promotes hair follicle regeneration and stem cell activation in an age-dependent manner by modulating inflammatory cells and oxidative stress in mice.
21 citations
,
June 2016 in “Reproductive Sciences”
This study found increased IL-18 levels in the endometrium of women with polycystic ovary syndrome, especially in those who are overweight, suggesting a link with body mass index.
Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.