learn Baricitinib
JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases
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Tracking 11 products like 113 FOLLICS FR16, 129 Recur Finasteride 1mg, 150 Brintop F Topical Solution, 154 Duprost and 155 Dutagen 0.5mg from by companies like Minoxidil Express and Inhouse Pharmacy. View all 11 products »Learn
5 / 23 resultslearn Tofacitinib
a JAK inhibitor for alopecia areata and other autoimmune conditions
learn Valproic acid
an anticonvulsant repurposed for hair loss via histone inhibition
learn Finasteride
Frontline, gold standard treatment for combatting androgenic alopecia
learn Dutasteride
Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
Research
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research Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP-Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor
Finasteride effectively blocks enzyme causing male pattern baldness.
research Inhibition of Human Steroid 5β-Reductase (AKR1D1) by Finasteride and Structure of the Enzyme-Inhibitor Complex
Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.
research GC–MS Profiling, Antioxidant, Enzyme Inhibition, Molecular Docking, and ADME Investigation of the n-Hexane Extract and the Essential Oil of Platycladus Orientalis (L.) Franco Fruits
Platycladus orientalis fruit extracts have antioxidant and enzyme-inhibiting properties, useful for health and food applications.
research In Silico Study of 12 Phytosterol Compounds in Moringa (Moringa Oleifera Lamk.) Seed Oil on 5α-Reductase Enzyme Inhibition Activity as Anti-Alopecia
Ergostadienol from Moringa seed oil may help prevent hair loss.
research Increase in Formalin-Induced Tonic Pain by 5α-Reductase and Aromatase Inhibition in Female Rats
Inhibiting certain enzymes made female rats more sensitive to low-level pain.
Community Join
5 / 1000+ resultscommunity Did anybody use beta sisterol for hair loss? I saw in many articles in the internet that said that beta sisterol blocks dht by inhibiting 5a reductase type 2 enzyme and some reviews of people who said that it worked better than saw palmetto in terms of stoping hair loss and helping prostate.
Beta-sitosterol may inhibit 5-alpha reductase type 2 enzyme, potentially reducing DHT levels and promoting hair growth, similar to finasteride but possibly with fewer side effects. Its effectiveness and side effects compared to other treatments like saw palmetto and finasteride remain uncertain due to limited research.
community ghk-cu is potent 5-ar inhibitor?
GHK-Cu is a potent inhibitor of the type 1 5-alpha reductase enzyme in hair follicles, which may reduce hair loss without the side effects associated with type 2 5-alpha reductase inhibitors. The user previously experienced side effects with 5-alpha reductase inhibitors and is considering GHK-Cu as an alternative.
community FCE 28260: A Forgotten 5α-Reductase Inhibitor
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community Painkillers May Block Minoxidil
Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.
community Has anyone here tried taking GLA supplements?
GLA may help with hair loss due to its anti-inflammatory properties and 5ar enzyme inhibition. It's considered potentially more important than biotin, especially for those already using finasteride and dutasteride.