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      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn Adenosine

      nucleoside used for hair regrowth stimulant properties

      learn Lavender

      plant and natural oil with antimicrobial and some anti-androgenic effects

      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

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      community Ultimate Hairloss Flowchart (for beginners)

      in Treatment  247 upvotes 1 year ago
      The conversation discusses a hair loss flowchart for beginners, with mixed opinions on its effectiveness. Treatments mentioned include minoxidil, finasteride, dutasteride, microneedling, and vitamins.

      community I've stopped taking finasteride. What now?

      in Finasteride  19 upvotes 6 years ago
      The user stopped taking finasteride due to side effects and is seeking alternative hair loss treatments; they currently use minoxidil and a caffeine shampoo. Suggestions include derma rolling to enhance minoxidil effectiveness and personal experiences of hair loss after stopping finasteride.

      community Which compounds in Saw Palmetto are actually beneficial?

      in Research/Science  2 upvotes 11 months ago
      Saw palmetto's fatty acids, particularly lauric and linoleic acids, inhibit enzymes linked to hair loss, while sterols like beta-sitosterol are less effective due to poor absorption. The conversation questions which specific compounds in saw palmetto contribute to its anti-androgenic effects.

      community The mechanism of androgenic alopecia

      in Research/Science  32 upvotes 2 weeks ago
      DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.