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GlossaryHair Follicle Infundibulum

upper part of the hair follicle extending to sebaceous gland

The hair follicle infundibulum is the upper part of the hair follicle, extending from the opening of the follicle at the skin's surface down to the point where the sebaceous (oil) gland attaches. This region is crucial for the passage of sebum and other substances to the skin's surface, and it plays a role in conditions like acne and folliculitis.

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research Microneedling Dilates the Follicular Infundibulum and Increases Transfollicular Absorption of Liposomal Sepia Melanin

25 citations, June 2015 in “Clinical, Cosmetic and Investigational Dermatology”

Microneedling helps increase the absorption of a melanin product into hair follicles, which may improve laser hair removal effectiveness.

research Upregulation of Interfollicular Epidermal and Hair Infundibulum β-Catenin Expression in Gsdma3 Mutant Mice

11 citations, June 2012 in “Acta histochemica”

Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.

research Tight Junction Barriers in Human Hair Follicles – Role of Claudin-1

39 citations, August 2018 in “Scientific reports”

Claudin-1 is important for the barrier function and growth of hair.

research Embryology, Histology, and Physiology of the Hair Follicle

1 citations, January 2017 in “Springer eBooks”

The document explains how hair follicles develop, their structure, and how they grow.

Dandruff Is Associated With Perturbations of Hair Follicle Immune Privilege and the Infundibular and Epidermal Immune Microenvironment

research Dandruff Is Associated With Perturbations of Hair Follicle Immune Privilege and the Infundibular and Epidermal Immune Microenvironment

November 2022 in “Journal of Investigative Dermatology”

Dandruff is linked to changes in the immune system of hair follicles and skin.

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community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 1 year ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Fibrosing alopecia in a pattern distribution

in Research/Science 14 upvotes 8 months ago

A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.