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    GlossaryInflammation (Inflammatory Process)

    body's natural response to injury or infection

    Inflammation is the body's natural response to injury or infection, characterized by redness, heat, swelling, and pain. It involves the activation of the immune system to eliminate harmful stimuli and initiate healing. While acute inflammation is a protective mechanism, chronic inflammation can lead to various health issues, including autoimmune diseases and tissue damage.

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      learn Baricitinib

      JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn Hydrocortisone

      a synthetic cortisol used for anti-inflammatory effects

      learn GHK-Cu

      a copper peptide showing promise in both regrowth and reversing gray hair

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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community A hill on which I will die: The DHT itch absolutely exists

      in Research/Science  210 upvotes 6 months ago
      The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.

      community I am actually regrowing my hairline without minoxidil or finasteride (mechanical stimulation)

       128 upvotes 6 years ago
      Regrowing hairline without the use of Minoxidil or Finasteride, and instead using mechanical stimulation such as Derma Roller, Nizoral, Zinc Pyrithione, Scalp Massage, Scalp Exercise, Fish Oil and other topical solutions. It is cautioned that there are risks associated with not using medically-prescribed treatments, but it is suggested to consider mechanical stimulation in addition to those prescribed treatments.

      community Creatine's effect on Hair Loss and DHT

      in Research/Science  101 upvotes 8 months ago
      A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.