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    GlossaryInflammation (Inflammatory Process)

    body's natural response to injury or infection

    Inflammation is the body's natural response to injury or infection, characterized by redness, heat, swelling, and pain. It involves the activation of the immune system to eliminate harmful stimuli and initiate healing. While acute inflammation is a protective mechanism, chronic inflammation can lead to various health issues, including autoimmune diseases and tissue damage.

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      learn Baricitinib

      JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp
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      learn Hydrocortisone

      a synthetic cortisol used for anti-inflammatory effects

      learn GHK-Cu

      a copper peptide showing promise in both regrowth and reversing gray hair

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      community What is this pigmentation around my follicles?

      in Chat  29 upvotes 2 weeks ago
      The conversation discusses potential causes of pigmentation around hair follicles, suggesting sebum buildup, autoimmune conditions, or dermatitis. Treatments mentioned include finasteride, dutasteride, and an anti-inflammatory diet, with a recommendation to consult a doctor for a proper diagnosis.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  827 upvotes 5 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community A hill on which I will die: The DHT itch absolutely exists

      in Research/Science  208 upvotes 8 months ago
      The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.