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GlossaryInflammatory Proteins

molecules that trigger and sustain the body's inflammatory response

Inflammatory proteins, also known as pro-inflammatory proteins, are molecules produced by the immune system that play a crucial role in initiating and sustaining inflammation. These proteins, such as cytokines and chemokines, help the body respond to infections and injuries by signaling immune cells to the affected area, but excessive or chronic production can lead to conditions like autoimmune diseases and chronic inflammation.

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Learn

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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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Research

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Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function

research Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function

17 citations , February 2015 in “Cell Death and Disease”

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

Umbilical Cord Mesenchymal Stem Cell-Derived Apoptotic Extracellular Vesicles Ameliorate Cutaneous Wound Healing in Type 2 Diabetic Mice via Macrophage Pyroptosis Inhibition

research Umbilical Cord Mesenchymal Stem Cell-Derived Apoptotic Extracellular Vesicles Ameliorate Cutaneous Wound Healing in Type 2 Diabetic Mice via Macrophage Pyroptosis Inhibition

4 citations , September 2023 in “Stem cell research & therapy”

Special particles from umbilical cord stem cells help heal skin wounds in diabetic mice by preventing certain immune cell death.

Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch+/- Mice

research Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch+/- Mice

8 citations , March 2014 in “American Journal of Pathology”

Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.

research Rice Bran Mineral Extract Increases the Expression of Anagen-Related Molecules in Human Dermal Papilla Through Wnt/Catenin Pathway

9 citations , January 2017 in “Food & Nutrition Research”

Rice bran mineral extract may help promote hair growth and prevent hair loss.

research Evaluation of a Novel Dry Eye Model Induced by Oral Administration of Finasteride

9 citations , October 2017 in “Molecular Medicine Reports”

Finasteride causes reduced tear flow and severe eye inflammation.

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Community Join

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community 1+ year oral dut and oral min. 2023 → 2025. No regrowth or stability, loss continues. I'm completely cooked and demoralized.

in Progress Pictures 76 upvotes 6 months ago

The user has been using oral dutasteride and minoxidil for over a year without regrowth or stability, and hair loss continues. Suggestions include checking for inflammation, considering a scalp biopsy, and trying microneedling, topical anti-androgens, or a hair transplant.

community I’ve lost about 50% of my hair in 5 months. This is after 2 years of fin

in Finasteride/Dutasteride 16 upvotes 1 year ago

The user is experiencing significant hair thinning and scalp discomfort after two years on finasteride and is considering switching to dutasteride. Another person suggests that scalp inflammation might be the cause and recommends a YouTube channel for more information.

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