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Glossary Induced Pluripotent Stem Cells

cells reprogrammed from adult cells to an embryonic-like state

Induced Pluripotent Stem Cells (iPSCs) are a type of stem cell that scientists create by reprogramming adult cells, such as skin or blood cells, to revert to an embryonic-like state. This process allows these cells to potentially develop into any type of cell in the body, making them valuable for research, regenerative medicine, and disease modeling.

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Research

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research Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients

198 citations , June 2013 in “Molecular psychiatry”

This study found that schizophrenia-derived neurons exhibited impaired differentiation and mitochondrial dysfunction, suggesting a potential link between these factors and neurodevelopmental processes in schizophrenia.

research Differentiation of Mouse Induced Pluripotent Stem Cells into a Multipotent Keratinocyte Lineage

101 citations , December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study reports the successful differentiation of mouse induced pluripotent stem cells into keratinocytes that can regenerate skin and its structures in an in vivo environment.

research Generation of folliculogenic human epithelial stem cells from induced pluripotent stem cells

99 citations , January 2014 in “Nature communications”

In this study, researchers developed a method to differentiate human iPSCs into cells that can generate all lineages of hair follicles, potentially aiding treatments for hair loss and skin disorders.

research Induced Pluripotent Stem Cells from Human Hair Follicle Mesenchymal Stem Cells

64 citations , December 2012 in “Stem Cell Reviews and Reports”

This study reports the successful generation of inducible pluripotent stem cells from mesenchymal stem cells derived from human hair follicles, marking a novel method of reprogramming these cells.

research Reprogramming of Human Hair Follicle Dermal Papilla Cells into Induced Pluripotent Stem Cells

26 citations , February 2012 in “Journal of Investigative Dermatology”

This study found that dermal papilla cells from human hair follicles can be reprogrammed into induced pluripotent stem cells, but their efficiency is similar to that of fibroblasts, unlike in mice.

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Community Join

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community Functional hair follicles grown from stem cells: Scientists have created natural-looking hair that grows through the skin using human induced pluripotent stem cells (iPSCs), a major scientific achievement that could revolutionize the hair growth industry.

171 upvotes 7 years ago

Scientists have grown natural-looking hair from stem cells, potentially revolutionizing hair growth treatments. Concerns include cost, DHT resistance, and the need for future procedures.

community Hair Multiplication Projects in China - Promising clinical trial results on Mice

34 upvotes 1 year ago

A breakthrough in hair follicle cultivation using induced pluripotent stem cells (iPSCs) has been achieved, producing large hair follicles suitable for transplantation. Clinical trials for this hair multiplication technology are planned in partnership with Yinguan Biotechnology.

community Anyone hear about Stemson's presentation at the 2021 Global Hair Loss Summit?

7 upvotes 4 years ago

Stemson's presentation discussed using induced pluripotent stem cell technology to create new hair follicles for treating hair loss. The conversation also mentions treatments like Minoxidil, finasteride, and RU58841.

community A Theory on Why Microneedling Works

175 upvotes 6 years ago

Microneedling may enhance hair regrowth by transferring stem cells to dormant follicles, improving the effects of minoxidil. Users discuss using microneedling with needle lengths around 1.5mm to stimulate hair growth.

community Please explain this Minoxidil phenomena

58 upvotes 2 years ago

The post discusses the difference in effects of Minoxidil (Min) on scalp and facial hair. The user questions why Min-induced hair growth on the scalp is temporary, while facial hair growth seems permanent, even after stopping Min. They propose theories, including different Min mechanisms on body and facial hair, the role of DHT, and the possibility of not achieving fully terminal hair. The responses include personal experiences and theories about Min's effects on hair growth.

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learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Apple stem cell

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