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research COVID-19: Understanding Inter-Individual Variability and Implications for Precision Medicine

58 citations , December 2020 in “Mayo Clinic Proceedings”

This paper discusses the variability in COVID-19 susceptibility and severity, emphasizing factors like biological differences and suggesting potential precision medicine approaches, but it reports no new clinical results.

research Five SNP variability in male pattern hair loss patients and healthy individuals from Russia

January 2019

Genetic differences may influence male pattern hair loss in Russians.

Individual Variation in Balance Between Platelet-Secreted Growth Factors Causing Contradictory Effects on Hair Follicle Could Potentially Impact Response to PRP Therapy in Patients With Scalp Hair Loss

research 878 Individual variation in balance between platelet-secreted growth factors causing contradictory effects on hair follicle could potentially impact response to PRP therapy in patients with scalp hair loss

1 citations , April 2018 in “Journal of Investigative Dermatology”

In this study, researchers found that the variability in growth factor expression, particularly TGFβ1, in PRP samples could influence patient responses to hair loss treatment with PRP therapy.

Electrophoretic Variability in Human Hair: Comparative Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis of Body and Head Hair Proteins

research Electrophoretic variability in human hair: Comparative sodium dodecyl sulfate‐polyacrylamide gel electrophoresis of body and head hair proteins

11 citations , January 1987 in “Electrophoresis”

This study found that keratin phenotypes were consistent across different types of hair from the same individual, allowing for successful keratin typing following ABH blood group determination.

research Food Administration and Not Genetic Variants Causes Pharmacokinetic Variability of Tadalafil and Finasteride

1 citations , October 2023 in “Journal of personalized medicine”

In this study, researchers investigated genetic variants in pharmacogenes affecting tadalafil and finasteride pharmacokinetics, finding fed volunteers had higher drug exposure than fasting individuals, but genetic variation did not significantly impact pharmacokinetics after correcting for multiple comparisons.

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Community Join

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community Last Post Before I Switch Back to Finasteride From Dutasteride

in Finasteride/Dutasteride 29 upvotes 1 year ago

The user plans to switch from dutasteride back to finasteride due to worsening hair loss, possibly due to increased scalp testosterone. Others report mixed results with both treatments, showing individual variability.

community 4 months on oral fin/min and I think I’m already seeing progress.

in Is this regrowth? 51 upvotes 1 year ago

A user reported seeing progress in hair regrowth after four months of using oral finasteride and minoxidil following a hair transplant. Others shared their experiences, noting improvements with these treatments, while some discussed the variability in results based on individual circumstances.

community NEW Creatine and DHT/Hairloss Study

9 upvotes 1 year ago

Creatine is believed by some users to cause hair shedding, though a study found no increase in DHT or testosterone levels. Many users shared personal experiences of hair loss after using creatine, while others noted no change, suggesting individual variability.

community Finasteride and male phenotypes

5 upvotes 11 years ago

Finasteride's effectiveness and side effects may vary based on male phenotypes, with some users noting differences in response related to body and facial hair characteristics. Some users report success with lower doses, while others experience side effects, suggesting individual variability in response to the treatment.

community Long-term use of dutasteride may lead to male infertility by persistently impairing semen volume and sperm motility.

in Finasteride/Dutasteride 87 upvotes 1 year ago

Long-term use of dutasteride may impair semen volume and sperm motility, but these effects are often reversible after stopping the drug. Individual reactions vary, and more research is needed to understand the long-term impact on fertility.

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Learn

6 / 801 results

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Mesotherapy

technique to inject very small amounts of beneficial chemicals into the scalp

learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Thymosin Beta 4

learn Follistatin

Is follistatin safe for use in women or transgender individuals undergoing hormone therapy? No study has tested follistatin in women or transgender people on hormone therapy, and it has no approved human use or established dose; the one relevant signal, from a 2023 randomized study in adolescents with PCOS, links higher follistatin to less favourable metabolic markers, so the published evidence does not support using it in this group.

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