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      community Why hasn’t anybody or any company done experiments on whether minoxidil and finasteride have effects on human collagen and elastin after a year of use compared to placebo? (In vivo not vitro)

       6 upvotes 7 months ago
      The conversation discusses the lack of in vivo studies on the effects of minoxidil and finasteride on human collagen and elastin after a year of use. It highlights the potential benefits of such research for understanding side effects and improving sales, despite challenges like cost and competition.

      community Any clinical study on cysteine alone for hair loss?

       6 upvotes 1 year ago
      The conversation discusses the lack of clinical studies on cysteine alone for hair loss, with the original poster already using medications like Minoxidil and finasteride. Suggestions include trying 2ddr as a growth stimulant, though concerns about side effects like gas are mentioned.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 2 years ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

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      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn Caffeine

      the stimulant you know and love can be used topically to stimulate hair

      learn Hydrocortisone

      a synthetic cortisol used for anti-inflammatory effects

      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles