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    Did you mean Immune Dysregulation?
    Glossary Immune Dysregulation

    malfunctioning immune system attacking body's own tissues

    Immune dysregulation refers to an imbalance or malfunction in the immune system, where it either overreacts, underreacts, or attacks the body's own tissues. This can lead to various health issues, including autoimmune diseases like alopecia areata, where the immune system mistakenly targets hair follicles, causing hair loss.

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    Research 10 of 1000+

    1. Proteomic Profiling of Central Centrifugal Cicatricial Alopecia Reveals Role of Humoral Immune Response Pathway and Metabolic Dysregulation JID Innovations · 2024 · 5 citations
    2. Primary cicatricial alopecias are characterized by dysregulation of shared gene expression pathways PNAS Nexus · 2022 · 19 citations
    3. Assessment of Cytokine-Mediated Signaling Pathway Dysregulation in Arm Skin After CO2 Laser Therapy Journal of lasers in medical sciences · 2019 · 13 citations
    4. Table 2_A meta-analysis of chemokines in alopecia areata: recruiting immune cells toward the hair follicle.docx Figshare · 2025
    5. Androgenetic alopecia risk in allergic rhinitis: A cohort study of immune and antihistamine effects World Allergy Organization Journal · 2026
    6. Table 1_Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata.docx Figshare · 2025
    7. Transcriptomic crossroads: Decoding genes and pathways that connect alopecia areata with chronic inflammatory skin disorders JID Innovations · 2026
    8. Precision therapeutics in non-scarring alopecia: a systemic genomic and pathway-based framework for targeted interventions ADMET & DMPK · 2025
    9. Papulopustular eruptions associated with EGFR-pathway-related targeted therapies: clinical spectrum, evidence boundaries, folliculocentric inflammation, and management considerations Frontiers in Oncology · 2026
    10. Environmental Modulation of JAK3-Mediated Immune Dysregulation in Alopecia Areata Scholarly Commons (Embry–Riddle Aeronautical University) · 2025
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    Learn 2 of 10

    1. Rapamycin Immune-suppressing drug, also called sirolimus
    2. Tofacitinib JAK inhibitor pill, an immune-system drug
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