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    Did you mean Immune Dysregulation?
    Glossary Immune Dysregulation

    malfunctioning immune system attacking body's own tissues

    Immune dysregulation refers to an imbalance or malfunction in the immune system, where it either overreacts, underreacts, or attacks the body's own tissues. This can lead to various health issues, including autoimmune diseases like alopecia areata, where the immune system mistakenly targets hair follicles, causing hair loss.

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    Research 30 of 1000+

    1. Proteomic Profiling of Central Centrifugal Cicatricial Alopecia Reveals Role of Humoral Immune Response Pathway and Metabolic Dysregulation JID Innovations · 2024 · 5 citations
    2. Primary cicatricial alopecias are characterized by dysregulation of shared gene expression pathways PNAS Nexus · 2022 · 19 citations
    3. Assessment of Cytokine-Mediated Signaling Pathway Dysregulation in Arm Skin After CO2 Laser Therapy Journal of lasers in medical sciences · 2019 · 13 citations
    4. Table 2_A meta-analysis of chemokines in alopecia areata: recruiting immune cells toward the hair follicle.docx Figshare · 2025
    5. Androgenetic alopecia risk in allergic rhinitis: A cohort study of immune and antihistamine effects World Allergy Organization Journal · 2026
    6. Table 1_Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata.docx Figshare · 2025
    7. Transcriptomic crossroads: Decoding genes and pathways that connect alopecia areata with chronic inflammatory skin disorders JID Innovations · 2026
    8. Precision therapeutics in non-scarring alopecia: a systemic genomic and pathway-based framework for targeted interventions ADMET & DMPK · 2025
    9. Papulopustular eruptions associated with EGFR-pathway-related targeted therapies: clinical spectrum, evidence boundaries, folliculocentric inflammation, and management considerations Frontiers in Oncology · 2026
    10. Environmental Modulation of JAK3-Mediated Immune Dysregulation in Alopecia Areata Scholarly Commons (Embry–Riddle Aeronautical University) · 2025
    11. 865 Frontal fibrosing alopecia is associated with dysregulation of cholesterol biosynthesis pathways, fibrosis and mast cells Journal of Investigative Dermatology · 2019
    12. LB923 A matched cohort study evaluating the risk of keloid development in alopecia areata patients Journal of Investigative Dermatology · 2024
    13. Erythrodermic Psoriasis in the Context of Emerging Triggers: Insights into Dupilumab-Associated and COVID-19-Induced Psoriatic Disease Dermatopathology · 2025
    14. Understanding the Association Between Mental Health and Hair Loss Cureus · 2025
    15. Vitiligo—Current Treatment Options and Future Perspectives International Journal of Molecular Sciences · 2026
    16. Alopecia Areata and Atopic Dermatitis: Common Mechanisms and Emerging Therapeutics Journal of Inflammation Research · 2026
    17. Bio-Nanovesicle-Based Approaches for Hair and Skin Regeneration: An Updated Concise Review Cells · 2026
    18. Comprehensive single-cell transcriptomic profiling of the scalp from patients with moderate-to-severe alopecia areata Journal of Allergy and Clinical Immunology · 2026
    19. Aberrant B cell and cytotoxic T cell activation in female pattern hair loss: a pilot comparative clinico-transcriptomic study Journal of Investigative Dermatology · 2025
    20. Exploring the potential of natural products in treating alopecia areata Journal of Pharmaceutical Analysis · 2026 · 1 citations
    21. Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata Frontiers in Immunology · 2025 · 4 citations
    22. Dermal T cell immunity and key regulatory signaling pathways: Implications in immune-mediated alopecia and hair regeneration Genes & Diseases · 2025 · 1 citations
    23. Table 1_A meta-analysis of chemokines in alopecia areata: recruiting immune cells toward the hair follicle.docx Figshare · 2025
    24. Healthy individuals genetically at-risk for the development of Pemphigus vulgaris or Alopecia areata share disease-like cytokine dysregulation Frontiers in Immunology · 2025 · 1 citations
    25. Image 1_A meta-analysis of chemokines in alopecia areata: recruiting immune cells toward the hair follicle.png Figshare · 2025
    26. 496 Identification of differentially expressed miRNAs in alopecia areata that target immune-regulatory pathways 2017
    27. Rapidly Progressive Alopecia Universalis after Varicella-Zoster Virus Infection: The role of Immune Dysregulation and Tofacitinib treatment 2025
    28. Paradoxical reactions in the era of modern biological therapy of psoriasis — a comprehensive analysis of pathomechanisms and clinical guidelines Forum Dermatologicum · 2026
    29. Transcriptome Meta-Analysis Confirms the Hidradenitis Suppurativa Pathogenic Triad: Upregulated Inflammation, Altered Epithelial Organization, and Dysregulated Metabolic Signaling Biomolecules · 2022 · 13 citations
    30. Immunological control of skin development: from homeostasis to developmental pathologies Frontiers in Immunology · 2025